|
|
| Property / cites work |
| | |
| Property / cites work: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate / rank |
| | Normal rank |
| Property / cites work: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt / rank |
| | Normal rank |
| Property / cites work: Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Direct control of the Forkhead transcription factor AFX by protein kinase B / rank |
| | Normal rank |
| Property / cites work: Direct control of the Forkhead transcription factor AFX by protein kinase B / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. / rank |
| | Normal rank |
| Property / cites work: Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B / rank |
| | Normal rank |
| Property / cites work: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway / rank |
| | Normal rank |
| Property / cites work: Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin / rank |
| | Normal rank |
| Property / cites work: Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. / rank |
| | Normal rank |
| Property / cites work: Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice / rank |
| | Normal rank |
| Property / cites work: An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway / rank |
| | Normal rank |
| Property / cites work: Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling / rank |
| | Normal rank |
| Property / cites work: Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth / rank |
| | Normal rank |
| Property / cites work: TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size / rank |
| | Normal rank |
| Property / cites work: Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb / rank |
| | Normal rank |
| Property / cites work: Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model / rank |
| | Normal rank |
| Property / cites work: Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Early clinical experience with a novel rapamycin derivative / rank |
| | Normal rank |
| Property / cites work: Early clinical experience with a novel rapamycin derivative / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. / rank |
| | Normal rank |
| Property / cites work: Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo / rank |
| | Normal rank |
| Property / cites work: The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes / rank |
| | Normal rank |
| Property / cites work: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Signal transduction to hypoxia-inducible factor 1 / rank |
| | Normal rank |
| Property / cites work: Signal transduction to hypoxia-inducible factor 1 / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: High frequency of mutations of the PIK3CA gene in human cancers / rank |
| | Normal rank |
| Property / cites work: High frequency of mutations of the PIK3CA gene in human cancers / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: PIK3CA is implicated as an oncogene in ovarian cancer. / rank |
| | Normal rank |
| Property / cites work: PIK3CA is implicated as an oncogene in ovarian cancer. / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. / rank |
| | Normal rank |
| Property / cites work: The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner / rank |
| | Normal rank |
| Property / cites work: Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy / rank |
| | Normal rank |
| Property / cites work: Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake / rank |
| | Normal rank |
| Property / cites work: Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Bcl-2 proto-oncogene expression in low- and high-grade prostatic intraepithelial neoplasia / rank |
| | Normal rank |
| Property / cites work: Bcl-2 proto-oncogene expression in low- and high-grade prostatic intraepithelial neoplasia / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression / rank |
| | Normal rank |
| Property / cites work: PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Mammalian target of rapamycin: a new molecular target for breast cancer / rank |
| | Normal rank |
| Property / cites work: Mammalian target of rapamycin: a new molecular target for breast cancer / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: The rapamycin-sensitive signal transduction pathway as a target for cancer therapy / rank |
| | Normal rank |
| Property / cites work: The rapamycin-sensitive signal transduction pathway as a target for cancer therapy / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Targeting HIF-1 for cancer therapy / rank |
| | Normal rank |
| Property / cites work: Targeting HIF-1 for cancer therapy / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. / rank |
| | Normal rank |
| Property / cites work: Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway / rank |
| | Normal rank |
| Property / cites work: Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway / reference |
| | |
| Property / cites work |
| | |
| Property / cites work: TSC2 regulates VEGF through mTOR-dependent and -independent pathways / rank |
| | Normal rank |
| Property / cites work: TSC2 regulates VEGF through mTOR-dependent and -independent pathways / reference |
| | |