mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. (Q44905183): Difference between revisions

From Wikidata
Jump to navigation Jump to search
Renamerr (talk | contribs)
Added [uk] description: наукова стаття, #quickstatements
Updated Item: Updating citation graph
Property / cites work
 
Property / cites work: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate / rank
 
Normal rank
Property / cites work: The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt / rank
 
Normal rank
Property / cites work: Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Direct control of the Forkhead transcription factor AFX by protein kinase B / rank
 
Normal rank
Property / cites work: Direct control of the Forkhead transcription factor AFX by protein kinase B / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. / rank
 
Normal rank
Property / cites work: Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B / rank
 
Normal rank
Property / cites work: Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway / rank
 
Normal rank
Property / cites work: Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin / rank
 
Normal rank
Property / cites work: Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. / rank
 
Normal rank
Property / cites work: Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice / rank
 
Normal rank
Property / cites work: An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway / rank
 
Normal rank
Property / cites work: Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling / rank
 
Normal rank
Property / cites work: Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth / rank
 
Normal rank
Property / cites work: TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size / rank
 
Normal rank
Property / cites work: Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb / rank
 
Normal rank
Property / cites work: Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model / rank
 
Normal rank
Property / cites work: Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Early clinical experience with a novel rapamycin derivative / rank
 
Normal rank
Property / cites work: Early clinical experience with a novel rapamycin derivative / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. / rank
 
Normal rank
Property / cites work: Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo / rank
 
Normal rank
Property / cites work: The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes / rank
 
Normal rank
Property / cites work: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Signal transduction to hypoxia-inducible factor 1 / rank
 
Normal rank
Property / cites work: Signal transduction to hypoxia-inducible factor 1 / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: High frequency of mutations of the PIK3CA gene in human cancers / rank
 
Normal rank
Property / cites work: High frequency of mutations of the PIK3CA gene in human cancers / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: PIK3CA is implicated as an oncogene in ovarian cancer. / rank
 
Normal rank
Property / cites work: PIK3CA is implicated as an oncogene in ovarian cancer. / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. / rank
 
Normal rank
Property / cites work: The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner / rank
 
Normal rank
Property / cites work: Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy / rank
 
Normal rank
Property / cites work: Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake / rank
 
Normal rank
Property / cites work: Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Bcl-2 proto-oncogene expression in low- and high-grade prostatic intraepithelial neoplasia / rank
 
Normal rank
Property / cites work: Bcl-2 proto-oncogene expression in low- and high-grade prostatic intraepithelial neoplasia / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression / rank
 
Normal rank
Property / cites work: PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Mammalian target of rapamycin: a new molecular target for breast cancer / rank
 
Normal rank
Property / cites work: Mammalian target of rapamycin: a new molecular target for breast cancer / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: The rapamycin-sensitive signal transduction pathway as a target for cancer therapy / rank
 
Normal rank
Property / cites work: The rapamycin-sensitive signal transduction pathway as a target for cancer therapy / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Targeting HIF-1 for cancer therapy / rank
 
Normal rank
Property / cites work: Targeting HIF-1 for cancer therapy / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. / rank
 
Normal rank
Property / cites work: Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway / rank
 
Normal rank
Property / cites work: Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0
Property / cites work
 
Property / cites work: TSC2 regulates VEGF through mTOR-dependent and -independent pathways / rank
 
Normal rank
Property / cites work: TSC2 regulates VEGF through mTOR-dependent and -independent pathways / reference
 
stated in: Crossref
reference URL: https://api.crossref.org/works/10.1038%2FNM1052
retrieved: 21 January 2018
Timestamp+2018-01-21T00:00:00Z
Timezone+00:00
CalendarGregorian
Precision1 day
Before0
After0

Revision as of 11:15, 25 October 2018

scientific article
Language Label Description Also known as
English
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
scientific article

    Statements

    mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. (English)
    Pradip K Majumder
    Timothy J McDonnell
    William R Sellers

    Identifiers