CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse (Q44973640)

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scientific article published on 11 July 2004

Language	Label	Description	Also known as
English	CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse	scientific article published on 11 July 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 December 2017

CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse (English)

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Europe PubMed Central

PubMed publication ID

7 December 2017

1 reference

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author name string

Qi-Jing Li

1

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Europe PubMed Central

PubMed publication ID

7 December 2017

Aaron R Dinner

2

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Europe PubMed Central

PubMed publication ID

7 December 2017

Shuyan Qi

3

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Darrell J Irvine

4

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Johannes B Huppa

5

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Mark M Davis

6

1 reference

Europe PubMed Central

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7 December 2017

Arup K Chakraborty

7

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7 December 2017

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publication date

11 July 2004

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7 December 2017

Nature Immunology

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7 December 2017

5

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PubMed publication ID

7 December 2017

8

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7 December 2017

791-799

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7 December 2017

Dynamics of Cell Surface Molecules During T Cell Recognition

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Direct observation of ligand recognition by T cells.

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Role of CD4 and CD8 in T cell activation and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

How the immune system works to protect the host from infection: a personal view

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Interaction between CD4 and class II MHC molecules mediates cell adhesion

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

CD4 dimers constitute the functional component required for T cell activation

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

An amplified sensitivity arising from covalent modification in biological systems

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Sensitivity amplification in biochemical systems

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Fluctuations and quality of control in biological cells: zero-order ultrasensitivity reinvestigated

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

A kinase-independent function of Lck in potentiating antigen-specific T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Dynamics of p56lck translocation to the T cell immunological synapse following agonist and antagonist stimulation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Linking molecular and cellular events in T-cell activation and synapse formation

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https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Dimeric association and segmental variability in the structure of human CD4

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Direct evidence for native CD4 oligomers in lymphoid and monocytoid cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

The immunological synapse balances T cell receptor signaling and degradation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Exact stochastic simulation of coupled chemical reactions

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Correlations between T-cell specificity and the structure of the antigen receptor

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

T-cell activation: the power of one.

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Kinetic proofreading in T-cell receptor signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Kinetic discrimination in T-cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Amino acid substitutions in the putative MHC class II "dimer of dimers" interface inhibit CD4+ T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

The structure of MHC class II: a role for dimer of dimers

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Detection of dimers of dimers of human leukocyte antigen (HLA)-DR on the surface of living cells by single-particle fluorescence imaging

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Interactions of CD4 with MHC class II molecules, T cell receptors and p56lck

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

A model for receptor-regulated calcium entry

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

21 January 2018

Selecting and maintaining a diverse T-cell repertoire

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

7 January 2021

based on heuristic

inferred from DOI database lookup

CD4 dimerization and oligomerization: implications for T-cell function and structure-based drug design

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

7 January 2021

based on heuristic

inferred from DOI database lookup

Activated TCRs remain marked for internalization after dissociation from pMHC

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI1095

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

ResearchGate publication ID

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