Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay (Q43655919)

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Language	Label	Description	Also known as
English	Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 November 2017

Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay (English)

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Europe PubMed Central

PubMed publication ID

25 November 2017

Paola Campomenosi

3

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25 November 2017

author name string

Maurici D

1

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25 November 2017

Monti P

2

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Europe PubMed Central

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25 November 2017

North S

4

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25 November 2017

Frebourg T

5

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25 November 2017

Fronza G

6

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25 November 2017

Hainaut P

7

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25 November 2017

language of work or name

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publication date

1 June 2001

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25 November 2017

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Europe PubMed Central

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25 November 2017

20

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25 November 2017

27

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25 November 2017

3533-3540

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PubMed publication ID

25 November 2017

Inactivation of the p53 protein in cell lines derived from human esophageal cancers

1 reference

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

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Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay

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WAF1, a potential mediator of p53 tumor suppression

1 reference

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21 January 2018

A simple p53 functional assay for screening cell lines, blood, and tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Screening thep53 status of human cell lines using a yeast functional assay

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Identification of p53 as a sequence-specific DNA-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Polyamine analogue-mediated cell cycle responses in human melanoma cells involves the p53, p21, Rb regulatory pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Stable reintroduction of wild-type P53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells

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21 January 2018

p53 is required for radiation-induced apoptosis in mouse thymocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progression through a p53-dependent pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Regulation of the p53 tumor suppressor protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Introduction: p53--the first twenty years

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Functional interaction between GCN5 and polyamines: a new role for core histone acetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Role of cysteine residues in regulation of p53 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

1 reference

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21 January 2018

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

1 reference

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21 January 2018

Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

21 January 2018

Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacological rescue of mutant p53 conformation and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Screening patients for heterozygous p53 mutations using a functional assay in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro antioxidant properties of amifostine (WR-2721, Ethyol)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Photoguides offer nurses an easy, cost-effective review

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

High frequency in esophageal cancers of p53 alterations inactivating the regulation of genes involved in cell cycle and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204428

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1204428

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

ResearchGate publication ID

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