Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. (Q42679830)

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scientific article published on December 2000

Language	Label	Description	Also known as
English	Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.	scientific article published on December 2000

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

S L Yean

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

G Wuenschell

2

1 reference

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3 November 2019

J Termini

3

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3 November 2019

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publication date

1 December 2000

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3 November 2019

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

408

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3 November 2019

6814

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3 November 2019

881-884

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3 November 2019

The question remains: is the spliceosome a ribozyme?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

A tertiary interaction that links active-site domains to the 5' splice site of a group II intron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Phosphorothioate substitution can substantially alter RNA conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Does a single metal ion bridge the A-9 and scissile phosphate groups in the catalytically active hammerhead ribozyme structure?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Mechanical devices of the spliceosome: motors, clocks, springs, and things

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

A second catalytic metal ion in group I ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Site-specific crosslinks of yeast U6 snRNA to the pre-mRNA near the 5' splice site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

The spliceosome is a dynamic ribonucleoprotein machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Metal ion catalysis in the Tetrahymena ribozyme reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

A general two-metal-ion mechanism for catalytic RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Ribozymes: A Distinct Class of Metalloenzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Split genes and RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

U6 snRNA function in nuclear pre-mRNA splicing: a phosphorothioate interference analysis of the U6 phosphate backbone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Thiophosphates in yeast U6 snRNA specifically affect pre-mRNA splicingin vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

27 May 2018

Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

16 August 2018

Metal coordination sites that contribute to structure and catalysis in the group I intron from Tetrahymena

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

16 August 2018

Metal ion catalysis during splicing of premessenger RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377090

1 December 2018

Catalytic site components common to both splicing steps of a group II intron

1 reference

https://pubmed.ncbi.nlm.nih.gov/11130730

12 December 2020

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10.1038/35048617

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11130730%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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