Generation and preclinical characterization of an antibody specific for SEMA4D. (Q42393761)

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scientific article published on 2 October 2015

Language	Label	Description	Also known as
English	Generation and preclinical characterization of an antibody specific for SEMA4D.	scientific article published on 2 October 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

Generation and preclinical characterization of an antibody specific for SEMA4D. (English)

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Europe PubMed Central

PMC publication ID

29 October 2017

author name string

Terrence L Fisher

1

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29 October 2017

Christine A Reilly

2

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29 October 2017

Laurie A Winter

3

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29 October 2017

Tracy Pandina

4

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29 October 2017

Alan Jonason

5

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29 October 2017

Maria Scrivens

6

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29 October 2017

Leslie Balch

7

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29 October 2017

Holm Bussler

8

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29 October 2017

Sebold Torno

9

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Europe PubMed Central

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29 October 2017

Jennifer Seils

10

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29 October 2017

Loretta Mueller

11

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29 October 2017

He Huang

12

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29 October 2017

Ekaterina Klimatcheva

13

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29 October 2017

Alan Howell

14

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29 October 2017

Renee Kirk

15

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Europe PubMed Central

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29 October 2017

Elizabeth Evans

16

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29 October 2017

Mark Paris

17

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29 October 2017

John E Leonard

18

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Europe PubMed Central

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29 October 2017

Ernest S Smith

19

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29 October 2017

Maurice Zauderer

20

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29 October 2017

publication date

2 October 2015

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Europe PubMed Central

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29 October 2017

Monoclonal Antibodies

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29 October 2017

8

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29 October 2017

1

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29 October 2017

150-162

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29 October 2017

Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Nonclinical Safety Evaluation of VX15/2503, a Humanized IgG4 Anti-SEMA4D Antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Ki-67 and CD100 immunohistochemical expression is associated with local recurrence and poor prognosis in soft tissue sarcomas, respectively

1 reference

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28 May 2018

Sema 4D/CD100-plexin B is a multifunctional counter-receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

The CD100 Receptor Interacts with Its Plexin B2 Ligand to Regulate Epidermal γδ T Cell Function

1 reference

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Pharmacokinetics and toxicology of therapeutic proteins: Advances and challenges

1 reference

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28 May 2018

Diverse roles for semaphorin-plexin signaling in the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Retracted: Plexin-B1 Activates NF-κB and IL-8 to Promote a Pro-Angiogenic Response in Endothelial Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Suppression of bone formation by osteoclastic expression of semaphorin 4D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

A novel Fc-engineered monoclonal antibody to CD37 with enhanced ADCC and high proapoptotic activity for treatment of B-cell malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Regulation of bone by the adaptive immune system in arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Biology and function of neuroimmune semaphorins 4A and 4D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Structural basis of semaphorin-plexin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Roles of Sema4D and Plexin-B1 in tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Guidance molecules in axon regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Regulation of immune cell responses by semaphorins and their receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Hypoxia-inducible factor-1-mediated regulation of semaphorin 4D affects tumor growth and vascularity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

When binding is enough: nonactivating antibody formats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Semaphorins and their receptors in immune cell interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Semaphorin CD100 from activated T lymphocytes induces process extension collapse in oligodendrocytes and death of immature neural cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

The semaphorin 4D receptor controls invasive growth by coupling with Met

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Generation of monoclonal antibodies specific for human kallikrein 2 (hK2) using hK2-expressing tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

The CD100-CD72 interaction: a novel mechanism of immune regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Biological activity of soluble CD100. I. The extracellular region of CD100 is released from the surface of T lymphocytes by regulated proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Identification of CD72 as a Lymphocyte Receptor for the Class IV Semaphorin CD100

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

28 May 2018

Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

16 August 2018

SEMA4D compromises blood-brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

16 August 2018

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

16 August 2018

Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

16 August 2018

Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

16 August 2018

The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

16 August 2018

The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966508

3 November 2018

Comparison of the ability of wild type and stabilized human IgG(4) to undergo Fab arm exchange with endogenous IgG(4)in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/26431358

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26431358

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26431358

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumours can act as adjuvants for humoral immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/26431358

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/26431358

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/19420862.2015.1102813

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

ResearchGate publication ID

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