Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma. (Q41663752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Frits van Rhee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Niels Weinhold

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Leo Rasche

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Shweta S Chavan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Caleb Stein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Owen W Stephens

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Ruslana Tytarenko

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Shayu Deshpande

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Purvi H Patel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Timea Buzder

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Gabor Molnar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Erich A Peterson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Sharmilan Thanendrarajan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Carolina Schinke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Erming Tian

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Joshua Epstein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Christoph J Heuck

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Maurizio Zangari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Bart Barlogie

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

language of work or name

English

0 references

publication date

11 August 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

1735-1744

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

A comprehensive survey of the mutagenic impact of common cancer cytotoxics

20 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Clinical value of molecular subtyping multiple myeloma using gene expression profiling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

SomaticSignatures: inferring mutational signatures from single-nucleotide variants.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Longitudinal analysis of 25 sequential sample-pairs using a custom multiple myeloma mutation sequencing panel (M(3)P).

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

A Big Bang model of human colorectal tumor growth

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3) P) in -17p high risk disease.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Curing myeloma at last: defining criteria and providing the evidence

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

The genetic architecture of multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Extramedullary myeloma whole genome sequencing reveals novel mutations in Cereblon, proteasome subunit G2 and the glucocorticoid receptor in multi drug resistant disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Clonal competition with alternating dominance in multiple myeloma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

The genetic architecture of multiple myeloma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

APOBEC3 proteins and genomic stability: the high cost of a good defense

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Initial genome sequencing and analysis of multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Double-hit B-cell lymphomas

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

The molecular classification of multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Analysis of PTEN deletions and mutations in multiple myeloma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5043128

18 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27516441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hypodiploidy is a major prognostic factor in multiple myeloma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27516441

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2016-06-723007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

27516441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27516441%20AND%20SRC:MED&resulttype=core&format=json