Acute exposure of methylglyoxal leads to activation of KATP channels expressed in HEK293 cells. (Q41502455)

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27 February 2020

title

Acute exposure of methylglyoxal leads to activation of KATP channels expressed in HEK293 cells (English)

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27 February 2020

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27 February 2020

Anuhya Sharma Konduru

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Ningren Cui

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27 February 2020

Lei Yu

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27 February 2020

Timothy C Trower

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27 February 2020

Weiwei Shi

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Yun Shi

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Chun Jiang

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publication date

14 October 2013

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Acta Pharmacologica Sinica

27 February 2020

published in

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volume

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issue

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page(s)

58-64

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Prolonged exposure to methylglyoxal causes disruption of vascular KATP channel by mRNA instability

27 February 2020

cites work

1 reference

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Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies

10 June 2018

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Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

10 June 2018

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Rosiglitazone inhibits vascular KATP channels and coronary vasodilation produced by isoprenaline.

10 June 2018

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Oxidative stress and aging: is methylglyoxal the hidden enemy?

10 June 2018

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Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

10 June 2018

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Methylglyoxal enhances sodium nitroprusside-induced relaxation in rat aorta

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Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits

10 June 2018

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Physiological roles of K+ channels in vascular smooth muscle cells

10 June 2018

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A short motif in Kir6.1 consisting of four phosphorylation repeats underlies the vascular KATP channel inhibition by protein kinase C.

10 June 2018

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PKA-dependent activation of the vascular smooth muscle isoform of KATP channels by vasoactive intestinal polypeptide and its effect on relaxation of the mesenteric resistance artery

10 June 2018

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Reactive carbonyls and oxidative stress: potential for therapeutic intervention

10 June 2018

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Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification

10 June 2018

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KATP channels as molecular sensors of cellular metabolism

10 June 2018

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10 June 2018

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The coronary circulation in diabetes: influence of reactive oxygen species on K+ channel-mediated vasodilation

10 June 2018

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Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels

10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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10 June 2018

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Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method

19 August 2018

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Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels

19 August 2018

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19 August 2018

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S-Glutathionylation underscores the modulation of the heteromeric Kir4.1-Kir5.1 channel in oxidative stress

19 August 2018

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12 December 2020

Glyoxalase System in Clinical Diabetes Mellitus and Correlation with Diabetic Complications

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12 December 2020

Metformin reduces systemic methylglyoxal levels in type 2 diabetes

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12 December 2020

Methylglyoxal accumulation in arterial walls causes vascular contractile dysfunction in spontaneously hypertensive rats

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12 December 2020

Identifiers

DOI

10.1038/APS.2013.122

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27 February 2020

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27 February 2020

PubMed publication ID

24122011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24122011%20AND%20SRC:MED&resulttype=core&format=json