Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia (Q40975402)

25 September 2017

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title

Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia (English)

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25 September 2017

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Y Ito

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25 September 2017

publication date

1 January 1996

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Journal of Cancer Research and Clinical Oncology

25 September 2017

published in

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25 September 2017

volume

122

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25 September 2017

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25 September 2017

page(s)

266-274

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Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain

25 September 2017

cites work

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12 December 2020

Leukaemia/Drosophila homology

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12 December 2020

Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter

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12 December 2020

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

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12 December 2020

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

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12 December 2020

The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

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12 December 2020

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system

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12 December 2020

Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia.

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12 December 2020

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

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12 December 2020

Two overlapping sequence motifs within the polyomavirus enhancer are independently the targets of stimulation by both the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the Ha-ras oncogene

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12 December 2020

Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer

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12 December 2020

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

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12 December 2020

Sequence specificity of the core-binding factor

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12 December 2020

Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines

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12 December 2020

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

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12 December 2020

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

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12 December 2020

Differential expression of subspecies of polyomavirus and murine leukemia virus enhancer core binding protein, PEBP2, in various hematopoietic cells

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12 December 2020

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

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12 December 2020

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

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12 December 2020

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

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12 December 2020

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers

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12 December 2020

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

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12 December 2020

Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias

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12 December 2020

Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins

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12 December 2020

Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide

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12 December 2020

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

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12 December 2020

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

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12 December 2020

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

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12 December 2020

Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

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12 December 2020

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

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12 December 2020

Cooperative binding of Ets-1 and core binding factor to DNA

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12 December 2020

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

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12 December 2020

A polyomavirus enhancer-binding protein, PEBP5, responsive to 12-O-tetradecanoylphorbol-13-acetate but distinct from AP-1.

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12 December 2020

Polyoma regulatory region: a potential probe for mouse cell differentiation

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12 December 2020

RETRACTED: The leukemic core binding factor beta-smooth muscle myosin heavy chain (CBF beta-SMMHC) chimeric protein requires both CBF beta and myosin heavy chain domains for transformation of NIH 3T3 cells

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12 December 2020

Alternative splicing and genomic structure of theAML1gene involved in acute myeloid leukemia

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12 December 2020

Translocation breakpoints are clustered on both chromosome 8 and chromosome 21 in the t(8;21) of acute myeloid leukemia.

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12 December 2020

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials

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12 December 2020

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

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12 December 2020

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity

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12 December 2020

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

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12 December 2020

Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2

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12 December 2020

AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

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12 December 2020

Involvement of the AML1 gene in the t(3;21) in therapy-related leukemia and in chronic myeloid leukemia in blast crisis

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12 December 2020

The Runt domain identifies a new family of heteromeric transcriptional regulators.

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12 December 2020

Identifiers

DOI

10.1007/BF01261402

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25 September 2017

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