miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression (Q40103209)

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English	miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

24 June 2018

http://europepmc.org/abstract/PMC/5576818

miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression (English)

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Europe PubMed Central

PMC publication ID

24 June 2018

http://europepmc.org/abstract/PMC/5576818

stem cell homeostasis

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Nathaniel Magilnick

1

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8 June 2020

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8 June 2020

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8 June 2020

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Estefany Y Reyes

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8 June 2020

Steven L Vonderfecht

4

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8 June 2020

Jun-Ichiro Inoue

6

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8 June 2020

Mark P Boldin

7

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8 June 2020

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7 August 2017

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24 June 2018

http://europepmc.org/abstract/PMC/5576818

Proceedings of the National Academy of Sciences of the United States of America

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8 June 2020

114

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8 June 2020

34

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8 June 2020

E7140-E7149

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8 June 2020

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11 June 2022

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based on heuristic

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Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

IFN-γ-mediated hematopoietic cell destruction in murine models of immune-mediated bone marrow failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Constitutive NF-κB activation in AML: Causes and treatment strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Altered lymphopoiesis and immunodeficiency in miR-142 null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Impact of interferon-γ on hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Role of microRNA-146a in normal and malignant hematopoietic stem cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Cytotoxic CD8+ T cells stimulate hematopoietic progenitors by promoting cytokine release from bone marrow mesenchymal stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

The p53 transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

miR-146a controls the resolution of T cell responses in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

MicroRNAs, new effectors and regulators of NF-κB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Bone marrow and the control of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Altered miR‐146a expression in Sjögren's syndrome and its functional role in innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Expression of microRNA-146 in rheumatoid arthritis synovial tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Structure and mechanism in NF-kappa B/I kappa B signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

1 reference

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25 June 2018

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

1 reference

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25 June 2018

TRAF6 is a signal transducer for interleukin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576818

25 June 2018

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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25 June 2018

Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo

1 reference

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25 June 2018

The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells

1 reference

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25 June 2018

Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population

1 reference

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20 August 2018

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

2 references

https://api.crossref.org/works/10.1073%2FPNAS.1706833114

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/28784800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/28784800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIGNAL TRANSDUCTION:IkB Kinases: Kinsmen with Different Crafts

1 reference

https://pubmed.ncbi.nlm.nih.gov/28784800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28784800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/28784800

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1706833114

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28784800%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28784800%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28784800%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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