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Prosthetic Joint Infection Due to Histoplasma capsulatum Complicating a Total Knee Arthroplasty

Open Forum Infect Dis. 2017 Aug 3;4(3):ofx118. doi: 10.1093/ofid/ofx118. eCollection 2017 Summer.

Abstract

Histoplasmosis is a common pathogen but rarely reported in prosthetic joint infections. We present a case of Histoplasmosis capsulatum prosthetic joint infection along with a literature review revealing no guidelines or consensus on surgical and antifungal management. We chose the 2-stage management with an antifungal spacer and systemic oral itraconazole.

Keywords: Histoplasma capsulatum; antifungal spacer; itraconazole; prosthetic joint infection; voriconazole.