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Lipschütz ulcer and group A streptococcal tonsillitis

BMJ Case Rep. 2018 Jun 6:2018:bcr2017223579. doi: 10.1136/bcr-2017-223579.

Abstract

Lipschütz ulcers (LU) are non-sexually related genital ulcers, rarely reported. We describe a healthy 11-year-old girl, who presented with fever and a painful vulvar ulcer associated with erythematous tonsillitis. Throat swab test for Group A Streptococcus (GAS) was positive. She was treated with amoxicillin. Further investigation was negative, including Herpes Simplex virus DNA from ulcer swab and serology for Epstein-Barr virus, cytomegalovirus and Mycoplasma pneumoniae Antistreptolysin O titre was high. The ulcer healed in 2 weeks, with no recurrence in a 1 year follow-up period. The association of LU with GAS tonsillitis is very rare.

Keywords: genital ulcers; immunology; medical education; mouth.

Publication types

  • Case Reports

MeSH terms

  • Amoxicillin / therapeutic use*
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Female
  • Fever
  • Humans
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / microbiology*
  • Streptococcal Infections / physiopathology
  • Tonsillitis / drug therapy
  • Tonsillitis / microbiology*
  • Treatment Outcome
  • Ulcer / drug therapy
  • Ulcer / microbiology*
  • Ulcer / physiopathology
  • Vulvar Diseases / drug therapy
  • Vulvar Diseases / microbiology*
  • Vulvar Diseases / physiopathology

Substances

  • Anti-Bacterial Agents
  • Amoxicillin