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proca protein C (inactivator of coagulation factors Va and VIIIa), a [ Salmo trutta (river trout) ]

Gene ID: 115156555, updated on 17-Mar-2024

Summary

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Gene symbol
proca
Gene description
protein C (inactivator of coagulation factors Va and VIIIa), a
See related
Ensembl:ENSSTUG00000035527
Gene type
protein coding
RefSeq status
MODEL
Organism
Salmo trutta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
Also known as
proc
Orthologs
human zebrafish all
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Genomic context

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See proca in Genome Data Viewer
Location:
chromosome: 21
Exon count:
10
Annotation release Status Assembly Chr Location
100 current fSalTru1.1 (GCF_901001165.1) 21 NC_042977.1 (5318741..5325671)

Chromosome 21 - NC_042977.1Genomic Context describing neighboring genes Neighboring gene S-antigen; retina and pineal gland (arrestin) a Neighboring gene inner ear-specific collagen-like Neighboring gene dual specificity phosphatase 28 Neighboring gene WD repeat domain 33

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_042977.1 Chromosome 21 Reference fSalTru1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vitamin K-dependent protein C
Names
protein C, inactivator of coagulation factors Va and VIIIa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Salmo trutta Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fSalTru1.1 Primary Assembly

Genomic

  1. NC_042977.1 Reference fSalTru1.1 Primary Assembly

    Range
    5318741..5325671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029704005.1 → XP_029559865.1  vitamin K-dependent protein C

    UniProtKB/TrEMBL
    A0A674CA76
    Related
    ENSSTUP00000080512.1, ENSSTUT00000085724.1
    Conserved Domains (4) summary
    cd00054
    Location:85 → 119
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00190
    Location:195 → 426
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam14670
    Location:128 → 165
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl02449
    Location:23 → 84
    Gla; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Nucleotide Protein
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