Enzymes articles from across Nature Portfolio

Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological catalysts, enzymes work by lowering a reaction’s activation energy barrier, thereby increasing the rate of the reaction. They also improve the specificity of the reactions.

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Sugar-modified nucleosides from simple ingredients

Enzymatic cascades enable the synthesis of sugar-modified nucleosides from bulk chemicals.
- Felix Kaspar
News & Views05 Nov 2024 Nature Synthesis
P: 1-2

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Synergistic photobiocatalysis for enantioselective triple radical sorting
- Zhongqiu Xing
- Fulu Liu
- Xiaoqiang Huang
Research21 Nov 2024 Nature
P: 1-3
Truncating the C terminus of formate dehydrogenase leads to improved preference to nicotinamide cytosine dinucleotide
- Xiaojia Guo
- Xueying Wang
- Zongbao K. Zhao
ResearchOpen Access20 Nov 2024 Scientific Reports
Volume: 14, P: 28701
Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection

TnpB protein from a thermophilic archaea has collateral ssDNA cleavage activity activated by high temperature that has been employed in developing a new fast and sensitive TnpB-based nucleic acid detection tool (TESD).
- Ying Xu
- Wen Yin
- Tao Liu
ResearchOpen Access20 Nov 2024 Communications Biology
Volume: 7, P: 1541
Effects of different straw return methods on soil properties and yield potential of maize
- Rui-Zhi Liu
- Qinggeer Borjigin
- Rui-Ping Li
ResearchOpen Access19 Nov 2024 Scientific Reports
Volume: 14, P: 28682
Tuning architectural organization of eukaryotic P450 system to boost bioproduction in Escherichia coli

Cytochrome P450 enzymes (P450s) and their redox partner cytochrome P450 reductase (CPR) often perform poorly in bioproduction of natural products by engineered prokaryotic microbes. Here, the authors report spatial architecture-guided P450-CPR assembly for improving the biosynthetic performance of both plant and human P450s in E. coli.
- Yikui Li
- Jie Li
- Ren Wang
ResearchOpen Access19 Nov 2024 Nature Communications
Volume: 15, P: 10009
Functionally overlapping intra- and extralysosomal pathways promote bis(monoacylglycero)phosphate synthesis in mammalian cells

Bis(monoacylglycero)phosphate (BMP) is an important component of late endosomal and lysosomal membranes. In this study, the authors show that both intra- and extralysosomal pathways can contribute to BMP synthesis.
- Dominik Bulfon
- Johannes Breithofer
- Robert Zimmermann
ResearchOpen Access16 Nov 2024 Nature Communications
Volume: 15, P: 9937

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News and Comment

Sugar-modified nucleosides from simple ingredients

Enzymatic cascades enable the synthesis of sugar-modified nucleosides from bulk chemicals.
- Felix Kaspar
News & Views05 Nov 2024 Nature Synthesis
P: 1-2
Post-translationally created hybrids
- Jan-Stefan Voeller
Research Highlights23 Oct 2024 Nature Catalysis
Volume: 7, P: 1055
Molecular glue modulates mitochondria
- Engi Hassaan
Research Highlights22 Oct 2024 Nature Chemical Biology
Volume: 20, P: 1388
A cerium-dependent photoenzyme
- Majda Bratovič
Research Highlights22 Oct 2024 Nature Chemical Biology
Volume: 20, P: 1387
Orthogonal redox control

The integration of a new orthogonal redox cofactor opens opportunities for controlling reaction equilibria. Because it does not interfere with cellular redox homeostasis, this approach enables the precise tuning of metabolic pathways and the optimization of microbial bioproduction, independently of canonical redox balancing.
- Lena M. Hümmler
- Steffen N. Lindner
News & Views24 Sept 2024 Nature Chemical Biology
Volume: 20, P: 1395-1396
Breaking down taurine
- Grant Miura
Research Highlights18 Sept 2024 Nature Chemical Biology
Volume: 20, P: 1237

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Enzymes articles from across Nature Portfolio

Featured

Sugar-modified nucleosides from simple ingredients

Related Subjects

Latest Research and Reviews

Synergistic photobiocatalysis for enantioselective triple radical sorting

Truncating the C terminus of formate dehydrogenase leads to improved preference to nicotinamide cytosine dinucleotide

Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection

Effects of different straw return methods on soil properties and yield potential of maize

Tuning architectural organization of eukaryotic P450 system to boost bioproduction in Escherichia coli

Functionally overlapping intra- and extralysosomal pathways promote bis(monoacylglycero)phosphate synthesis in mammalian cells

News and Comment

Sugar-modified nucleosides from simple ingredients

Post-translationally created hybrids

Molecular glue modulates mitochondria

A cerium-dependent photoenzyme

Orthogonal redox control

Breaking down taurine

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