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The influenza viruses cause respiratory tract infections in vertebrates – the ‘flu’ – and are responsible for seasonal epidemics in humans. The two main subtypes of virus, A & B, are highly virulent, with Influenza A carrying a great zoonotic potential. Highly susceptible to mutation, and easily transmitted through both the air and direct contact, each epidemic brings the need for careful disease mapping, and adapting of healthcare strategies, in order to mitigate the risk of transmission. Although often a manageable disease, complications such as pneumonia can occur that make this disease deadly. This collection showcases some of the best and latest research concerning this highly adaptable virus.