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Genetics

Genetics brings new insight to β-cell function

Nature Metabolism volume 6, pages 1848–1849 (2024)Cite this article

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A meta-analysis of genome-wide association study for eight traits related to pancreatic β-cell function, based on 26,000 individuals, identified 55 independent association signals mapping to 44 loci. This study highlighted new effectors of β-cell function.

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Fig. 1: Modeling BCF traits and their regulome across human tissues.

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Acknowledgements

A.B. is supported by the European Research Council (ERC OpiO – 101043671).

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Authors and Affiliations

  1. Université de Lille, Inserm UMR1283, CNRS UMR8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France

    Amélie Bonnefond & Philippe Froguel

  2. Department of Metabolism, Imperial College London, London, UK

    Amélie Bonnefond & Philippe Froguel

Authors
  1. Amélie Bonnefond
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  2. Philippe Froguel
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Correspondence to Amélie Bonnefond or Philippe Froguel.

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The authors declare no competing interests.

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Bonnefond, A., Froguel, P. Genetics brings new insight to β-cell function. Nat Metab 6, 1848–1849 (2024). https://doi.org/10.1038/s42255-024-01131-7

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