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KEGG   Ovis aries (sheep): 101118179
Entry
101118179         CDS       T03117                                 
Symbol
GRIN2B
Name
(RefSeq) glutamate receptor ionotropic, NMDA 2B
  KO
K05210  glutamate receptor ionotropic, NMDA 2B
Organism
oas  Ovis aries (sheep)
Pathway
oas04014  Ras signaling pathway
oas04015  Rap1 signaling pathway
oas04020  Calcium signaling pathway
oas04024  cAMP signaling pathway
oas04080  Neuroactive ligand-receptor interaction
oas04713  Circadian entrainment
oas04720  Long-term potentiation
oas04724  Glutamatergic synapse
oas04728  Dopaminergic synapse
oas05010  Alzheimer disease
oas05014  Amyotrophic lateral sclerosis
oas05016  Huntington disease
oas05017  Spinocerebellar ataxia
oas05020  Prion disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05030  Cocaine addiction
oas05031  Amphetamine addiction
oas05033  Nicotine addiction
oas05034  Alcoholism
oas05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101118179 (GRIN2B)
   04015 Rap1 signaling pathway
    101118179 (GRIN2B)
   04024 cAMP signaling pathway
    101118179 (GRIN2B)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    101118179 (GRIN2B)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    101118179 (GRIN2B)
   04728 Dopaminergic synapse
    101118179 (GRIN2B)
   04720 Long-term potentiation
    101118179 (GRIN2B)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101118179 (GRIN2B)
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    101118179 (GRIN2B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101118179 (GRIN2B)
   05014 Amyotrophic lateral sclerosis
    101118179 (GRIN2B)
   05016 Huntington disease
    101118179 (GRIN2B)
   05017 Spinocerebellar ataxia
    101118179 (GRIN2B)
   05020 Prion disease
    101118179 (GRIN2B)
   05022 Pathways of neurodegeneration - multiple diseases
    101118179 (GRIN2B)
  09165 Substance dependence
   05030 Cocaine addiction
    101118179 (GRIN2B)
   05031 Amphetamine addiction
    101118179 (GRIN2B)
   05033 Nicotine addiction
    101118179 (GRIN2B)
   05034 Alcoholism
    101118179 (GRIN2B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:oas04040]
    101118179 (GRIN2B)
Ion channels [BR:oas04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   101118179 (GRIN2B)
SSDB
Motif
Pfam: NMDAR2_C Lig_chan Lig_chan-Glu_bd ANF_receptor SBP_bac_3
Other DBs
NCBI-GeneID: 101118179
NCBI-ProteinID: XP_027823652
LinkDB
Position
3:201476037..202004971
AA seq 1497 aa
MKPRAECCSPKFWLVLAVLAVSGSRARSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFH
HLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTL
TPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQ
DFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYI
FEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLVSVSYDEWDYGLPARVRDGIAII
TTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHP
KLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVE
SVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYL
VTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSR
SNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSF
TIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYV
DQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLS
LKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAI
LQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEH
LFYWQFRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILR
LLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFS
DYISEVERTFGNLQLKDSNVYQDHYHHHHRPHSIGSASSIDGLYDCDNPPFTTQPRALGK
KPLDIGLPSSKHSQLGDLYGKFSFKSDRYGGHDDLIRSDVSDISTHTVTYGNIEGNAAKR
RKQQYKDSLKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKDGLRDFYLDQFRAK
ETSPHWEHVDLTDLYKERGEDFKRDSVGGGGPCTNRAHHLKHGTGDKHGGGVVGGVPAPW
EKNLTNVDWEERPGGNFCRSCPSKLHNYSTTTAATAVVAGQNSGRPACIRCEACKKAGNL
YDISEDNSLQELDQPAAPVAAVTSAASKYPQSPTNSKAQKKPRNKLRRQHSYDTFVDLQK
EEAALAPRSVSLKDKGRFLDGSPYAHMFEMPAGESAFSGSNDGKAAAPAAGHHHHGNPGG
GGGYMLSKSLYPDRVTQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGAPKARPDFRALVSN
KPVVSALHGAVPGRFQKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV
NT seq 4494 nt   +upstreamnt  +downstreamnt
atgaagcccagagcggagtgctgttcccccaagttctggttggtgctggctgtcctggcc
gtgtccggcagcagagctcgttctcagaagagcccgcccagcataggcattgctgtcatc
ctcgtgggcacttcagacgaggtggccatcaaggacgcccacgagaaagatgatttccac
catctctctgtggtgccccgcgtggagctggtggccatgaacgagacggacccaaagagc
atcataacccgcatctgtgatctcatgtccgaccggaagatccagggggtggtgtttgct
gatgacacagaccaggaagccatcgcccagatccttgacttcatttcagcccagactctc
acccccatcctgggcatccacgggggctcctcgatgataatggcggacaaggatgaatcc
tccatgttcttccagttcggcccgtccattgaacagcaggcttccgtgatgctcaacatc
atggaggagtatgactggtacatcttctctatcgtcaccacctacttccctggctaccag
gacttcgtcaacaagattcgcagcaccatcgagaacagcttcgtgggctgggagctggag
gaggtccttctgctggacatgtccttggacgacggggattctaaaatccagaaccagctc
aagaaactccagagccccatcattcttctttactgtactaaggaagaggccacctacatc
ttcgaagtggctaactcagtagggctgaccggctacggctacacgtggattgtgcctagt
ctggtggcgggggacacggacacagtgccctcggagttccccaccggcctggtctctgtg
tcctatgatgagtgggactacggcctccctgccagagtgagggacgggatcgccatcatc
accaccgcggcctctgacatgctgtcggaacacagcttcatccccgagcccaagagcagc
tgctacaacacccacgagaagaggatctaccagtccaatatgctgaacaggtatctgatc
aatgtgacttttgaagggagaaatctgtccttcagtgaagacggctaccagatgcaccca
aagctggtgatcatccttctgaacaaggagaggaagtgggagagggtagggaagtggaaa
gacaagtccctgcagatgaagtactacgtgtggccccgaatgtgtcctgagacagaagag
caggaggatgaccacttgagcatcgtaacactggaggaagccccattcgtcattgtggag
agcgtggaccctctgagtggaacctgcatgaggaacacggtcccctgccaaaagcgcatc
atctccgaaaataaaacagatgaggagccaggttacatcaaaaagtgctgcaaggggttc
tgtattgatatccttaagaagatttctaaatctgtgaagttcacctatgatctttacctc
gttaccaacggcaagcacgggaagaaaatcaatggaacctggaatggtatgattggagag
gtggtcatgaagagggcctacatggcagtggggtcgctgaccatcaacgaggagcgatca
gaggtggtcgatttctccgtgcccttcatagagactggcatcagcgtcatggtgtcacgc
agcaatgggaccgtttcaccttctgccttcttagagccattcagcgctgacgtgtgggtc
atgatgtttgtgatgctcctcatcgtctcggccgtggccgtctttgtcttcgagtacttt
agccccgtgggttacaacaggtgcctcgctgacggcagagagccaggtggcccatctttc
accatcggcaaagctatttggttactgtggggtctggtgtttaacaactccgtccccgtg
cagaaccccaagggtaccacgtccaagatcatggtgtccgtgtgggccttctttgccgtc
atcttcctggccagctacactgccaacttagctgccttcatgatccaagaggagtatgtg
gaccaggtttccggcctgagtgacaagaagttccagagacctaatgacttctcaccccct
ttccgctttggcactgtgcccaatggcagcacggagaggaatattcgcaataactatgca
gaaatgcatgcctacatggggaagtttaaccagagaggtgtcgatgatgcactgctctcc
ctgaaaacagggaaactggatgccttcatctatgatgcagccgtgctgaactacatggcc
ggtagagatgagggctgcaagctggtgaccattggcagtgggaaggtctttgcctccact
ggttatggcattgccatccaaaaagactctggatggaagcgccaggtggaccttgctatc
ctgcagctcttcggagatggggagatggaggagctggaagctctgtggctcacaggcatc
tgccacaatgagaagaacgaggtcatgagtagccagctggacattgacaacatggcgggc
gtcttctacatgctgggggccgccatggctctcagcctcatcaccttcatctgcgaacac
ctcttctattggcagttccggcactgctttatgggtgtctgttctggcaagcccggcatg
gtcttctccatcagcagaggtatctacagctgcatccacggcgtggccattgaggagcgc
caatccgtgatgaactcccccaccgccaccatgaacaacacgcactccaatatcctgcgt
ctgctgcgcacggccaagaacatggccaacctgtcgggtgtgaatggctcaccgcagagc
gccctggacttcatccgccgcgagtcgtctgtctatgacatctccgagcaccgccgcagc
ttcacgcactccgactgcaagtcctacaataacccgccctgcgaggagaacctgttcagc
gactacatcagtgaggtggaaaggactttcgggaacctgcagctcaaggacagcaacgtc
taccaggaccactaccaccaccaccaccggccccacagcatcggcagcgccagctccata
gatgggctctatgactgcgacaacccgcccttcaccacgcagccccgggccctgggcaag
aagcccctggacattggccttccctcgtccaagcacagccagctcggcgacctgtacggc
aagttctcgttcaagagtgaccgctatggcggccacgacgacctgatccgctccgacgtg
tcagacatctccacccacacggtcacctatggcaacatcgagggcaacgcggccaagaga
cggaagcaacagtacaaggacagcctgaagaagcgtccggcctcagccaagtcccgccgc
gagttcgacgagatagagctggcctaccgccgccggccgccccgctccccagaccacaag
cgctactttcgggacaaggacgggctgcgggacttctacctggaccagttccgtgccaag
gagacctcgccgcactgggagcacgtggacctgaccgacctctacaaggagcgtggcgag
gatttcaagcgtgactcggtgggtggtggagggccctgtaccaaccgagctcatcatctt
aagcacggcacaggcgacaagcacggcgggggggtcgtcggcggggtcccggccccctgg
gagaagaacctgaccaacgtggactgggaggagcgccctgggggcaacttctgccgcagc
tgcccatccaagctgcacaactactcaacgacgacagcagcaacggcggtggtggctggc
cagaactcgggcaggccggcctgcatccgctgcgaggcgtgcaagaaggccggcaacctg
tacgacatcagcgaggacaactcgctgcaggagttggatcagccggccgccccagtggcg
gccgtgacgtccgcagcgtctaagtacccgcagagccctaccaactccaaggcacagaag
aagccccggaacaagctgcggcgccaacactcctacgacacgttcgtggacctgcagaaa
gaagaggccgccctggccccacgcagcgtgagcctcaaggacaagggccgcttcctggac
ggcagcccctacgcgcacatgttcgagatgccggcaggcgagagcgctttcagtggcagc
aacgatggcaaggcggcggcgccagccgcgggacatcaccaccacggcaatcccggcggc
ggcggtggctacatgctcagcaagtctctctaccccgaccgggtcacgcagaaccctttc
atccccactttcggggacgaccagtgcttgctccacggcagcaaatcctacttcttcagg
cagcccacggtggctggggcgccgaaggccaggccggacttccgggcccttgtgagcaac
aagccggtggtctcggccctgcacggggctgtgccgggccgcttccagaaagacatctgt
atagggaaccagtccaacccctgtgtgcctaacaacaaaaaccccagggctttcaatggc
tccagcaatgggcatgtgtatgagaaactgtctagtattgagtctgatgtctga

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