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KEGG   Mus caroli (Ryukyu mouse): 110291001
Entry
110291001         CDS       T05910                                 
Symbol
Pde5a
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
  KO
K13762  cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal00230  Purine metabolism
mcal01100  Metabolic pathways
mcal04022  cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    110291001 (Pde5a)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    110291001 (Pde5a)
Enzymes [BR:mcal01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     110291001 (Pde5a)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 DUF6970 HD-CE
Other DBs
NCBI-GeneID: 110291001
NCBI-ProteinID: XP_021013597
Ensembl: MGP_CAROLIEiJ_G0025596
UniProt: A0A6P5PDY2
LinkDB
Position
3:116257741..116382694
AA seq 865 aa
MERAGPSSVRSQQQRDPDWVEAWLDDHRDFTFSYFVRKATRDMVNAWFSERVHNIPVCKE
GMRAHTESCSCSLQQSPHADNTTPGAPARKISASEFDRPLRPIVVKDSEGTVSFLSDSGK
KEQMPLTPPRFDSDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSKDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCPDSFSRVFHMECEEVGRPSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKD
KRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQG
DRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNR
QKWQALAEQQEKMLLNGESSQGKRE
NT seq 2598 nt   +upstreamnt  +downstreamnt
atggaacgagcgggccccagctccgttcggtcgcagcagcagcgggacccggactgggtg
gaagcgtggctggatgatcaccgggactttaccttctcttactttgttagaaaggccacc
agagacatggtcaacgcatggttttcagagagagttcacaacatccctgtgtgtaaggaa
ggcatgcgagcccataccgagtcctgctcttgctctctgcagcaaagtcctcatgcagat
aataccacccctggagcaccagccagaaaaatatctgcctctgaatttgaccgacctctt
agacccattgttgtcaaggattccgagggaacagtgagctttctctctgactcaggaaaa
aaggagcagatgccactaaccccgccaagatttgatagtgatgaaggggaccagtgctca
agactcttggagctagtaaaagatatatccagtcatttggatgtcacagcattgtgccac
aaaattttcttgcatatccatggactcatctctgcggatcgctattccctgttccttgtc
tgcgaggacagctctaaagacaaattcctcatcagccgcctctttgatgttgctgaaggt
tcaacactggaggaagcttcaaataactgtatccgtttagagtggaacaaaggcattgtg
ggacatgtggcagcttttggtgagcccttgaacatcaaagatgcctatgaggatccccgg
ttcaatgcagaagttgaccaaattacaggctacaagacacaaagtatcctttgtatgcca
attaagaaccacagggaagaggttgttggtgtagctcaggccatcaacaagaaatcagga
aatggtgggaccttcactgaaaaagatgaaaaggactttgcggcctacctggcattctgt
ggtattgttcttcacaatgctcagctctacgaaacgtcgctgctggagaacaaaagaaat
caggtgttacttgaccttgcgagcttaatctttgaagagcagcagtccctggaagtcatt
ctgaagaagatcgctgccactatcatctccttcatgcaggtgcagaagtgcaccatcttc
attgtggatgaagactgtcctgactctttctctcgtgtgtttcacatggagtgtgaggaa
gtagggagaccctccgatcctttaacgagggagcaagatgcaaacaaaatcaactacatg
tatgcccagtatgtcaaaaacacgatggagccacttaatatcccagatgtcaccaaggac
aaaagatttccctggacaaatgaaaacatgggacacgtgaacacgccctgcattggaagt
ttactttgcacccctataaaaaacgggaagaagaacaaagtcataggcgtttgccaactt
gttaataagatggaggagaatactggcaagattaaagctttcaaccaaaatgatgagcag
ttcctggaagcctttgtcatcttctgtggcttggggatccagaacacacagatgtatgaa
gcagtggagagagccatggccaagcagatggtgacattagaggtcctgtcttaccatgca
tcagcggcggaggaagaaacaagagagctccaggctttatcggctgctgtggtaccatcg
gcccaaacccttaaaattaccgacttcagcttcagtgactttgagctgtctgatctggaa
acagcactgtgtacaattcggatgttcactgacctcaaccttgtgcagaatttccagatg
aaacatgaggttctttgcaggtggattttaagtgtgaagaagaattatcggaagaacgtt
gcctaccacaattggaggcatgcctttaacacggcacagtgcatgtttgctgctctgaaa
gccggcaagatccagaacaagttgacggatctggagatccttgcgttgctgattgctgct
ttaagccatgacttggatcatcgtggcgtgaacaactcatacatacagcggagcgagcac
ccgctggctcagctgtactgtcactccatcatggaacaccatcattttgaccagtgtttg
atgattctaaacagcccaggcaaccagattctcagtggcctctccattgaagaatataaa
accacattgaaaataatcaagcaagcaattttagccacagacctagcactgtacattaag
agacgaggagaattttttgaacttatacgaaaaaatcaattcagttttgaagatcctctt
caaaaggagttgtttctagcaatgctgatgacagcctgcgacctctctgcgattactaaa
ccctggcctattcaacaacggatagcagaactcgtggcagctgaattctttgaccaagga
gacagagagagaaaagaactgaacatggagccggctgatctaatgaacagagagaagaaa
aacaaaatcccaagtatgcaagttgggttcatagatgccatctgcttgcagctgtatgag
gccctgacccacgtatccgaagactgtttgcccttgctggatggctgcaggaagaacaga
cagaaatggcaggccctggcggagcagcaggagaagatgctccttaacggggagagcagc
cagggcaagcgggaatga

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