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Homo sapiens (human): 7357
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Entry
7357 CDS
T01001
Symbol
UGCG, GCS, GLCT1
Name
(RefSeq) UDP-glucose ceramide glucosyltransferase
KO
K00720
ceramide glucosyltransferase [EC:
2.4.1.80
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00600
Sphingolipid metabolism
hsa01100
Metabolic pathways
Module
hsa_M00066
Lactosylceramide biosynthesis
Network
nt06014
Sphingolipid degradation
Element
N00679
Glucosylceramide synthesis in GBA deficiency
Drug target
Eliglustat (
DG00148
):
D09893
D09894
<JP/US>
Lucerastat:
D11439
Miglustat:
D05032
<JP/US>
Venglustat (
DG03067
):
D11633
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
7357 (UGCG)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
hsa01003
]
7357 (UGCG)
Enzymes [BR:
hsa01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.80 ceramide glucosyltransferase
7357 (UGCG)
Glycosyltransferases [BR:
hsa01003
]
Glycolipid biosynthesis
Glycosphingolipid
7357 (UGCG)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_transf_21
Glyco_tranf_2_3
Glyco_trans_2_3
Glycos_transf_2
Chitin_synth_2
Motif
Other DBs
NCBI-GeneID:
7357
NCBI-ProteinID:
NP_003349
OMIM:
602874
HGNC:
12524
Ensembl:
ENSG00000148154
UniProt:
Q16739
LinkDB
All DBs
Position
9:111896814..111935369
Genome browser
AA seq
394 aa
AA seq
DB search
MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
AATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
KAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMT
IYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
NT seq
1185 nt
NT seq
+upstream
nt +downstream
nt
atggcgctgctggacctggccttggagggaatggccgtcttcgggttcgtcctcttcttg
gtgctgtggctgatgcatttcatggctatcatctacacccgattacacctcaacaagaag
gcaactgacaaacagccttatagcaagctcccaggtgtctctcttctgaaaccactgaaa
ggggtagatcctaacttaatcaacaacctggaaacattctttgaattggattatcccaaa
tatgaagtgctcctttgtgtacaagatcatgatgatccagccattgatgtatgtaagaag
cttcttggaaaatatccaaatgttgatgctagattgtttataggtggcaaaaaagttggc
attaatcctaaaattaataatttaatgccaggatatgaagttgcaaagtatgatcttata
tggatttgtgatagtggaataagagtaattccagatacgcttactgacatggtgaatcaa
atgacagaaaaagtaggcttggttcacgggctgccttacgtagcagacagacagggcttt
gctgccaccttagagcaggtatattttggaacttcacatccaagatactatatctctgcc
aatgtaactggtttcaaatgtgtgacaggaatgtcttgtttaatgagaaaagatgtgttg
gatcaagcaggaggacttatagcttttgctcagtacattgccgaagattactttatggcc
aaagcgatagctgaccgaggttggaggtttgcaatgtccactcaagttgcaatgcaaaac
tctggctcatattcaatttctcagtttcaatccagaatgatcaggtggaccaaactacga
attaacatgcttcctgctacaataatttgtgagccaatttcagaatgctttgttgccagt
ttaattattggatgggcagcccaccatgtgttcagatgggatattatggtatttttcatg
tgtcattgcctggcatggtttatatttgactacattcaactcaggggtgtccagggtggc
acactgtgtttttcaaaacttgattatgcagtcgcctggttcatccgcgaatccatgaca
atatacatttttttgtctgcattatgggacccaactataagctggagaactggtcgctac
agattacgctgtgggggtacagcagaggaaatcctagatgtataa
DBGET
integrated database retrieval system