Homo sapiens (human): 6476 Help Entry 6476              CDS       T01001                                  Symbol SI Name (RefSeq) sucrase-isomaltase   KO K01203   sucrase-isomaltase [EC:3.2.1.48 3.2.1.10] Organism hsa  Homo sapiens (human) Pathway hsa00052   Galactose metabolism hsa00500   Starch and sucrose metabolism hsa01100   Metabolic pathways hsa04973   Carbohydrate digestion and absorption Disease H00115   Congenital sucrase-isomaltase deficiency Drug target Camiglibose:  D03342 Sacrosidase:  D05782<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00052 Galactose metabolism     6476 (SI)    00500 Starch and sucrose metabolism     6476 (SI)  09150 Organismal Systems   09154 Digestive system    04973 Carbohydrate digestion and absorption     6476 (SI)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     6476 (SI) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.10  oligo-1,6-glucosidase      6476 (SI)     3.2.1.48  sucrose alpha-glucosidase      6476 (SI) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    6476 (SI) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glyco_hydro_31_2nd Glyco_hydro_31_3rd Gal_mutarotas_2 Trefoil Motif Other DBs NCBI-GeneID:  6476 NCBI-ProteinID:  NP_001032 OMIM:  609845 HGNC:  10856 Ensembl:  ENSG00000090402 UniProt:  P14410 Structure PDBPDBj LinkDB All DBs Position 3:complement(164978898..165090232) Genome browser AA seq 1827 aa AA seqDB search MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDS GKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMT TTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEF TGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYG IGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSN AMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRW NYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQ KYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNP NCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMY SKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAH WLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSR NHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHE FYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDM YLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDT IQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN AHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGC VWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRV EVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRS SGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPP GYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGP TPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDI DYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVF VKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVD FYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEA EQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGD NYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNI ANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKP TWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDT INLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLY LSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNE DTTNMILRIDLTTHNVTLEEPIEINWS NT seq 5484 nt NT seq  +upstreamnt  +downstreamnt atggcaagaaagaaatttagtggattggaaatctctctgattgtcctttttgtcatagtt actataatagctattgccttaattgttgttttagcaactaagacacctgctgttgatgaa attagtgattctacttcaactccagctactactcgtgtgactacaaatccttctgattca ggaaaatgtccaaatgtgttaaatgatcctgtcaatgtgagaataaactgcattccagaa caattcccaacagagggaatttgtgcacagagaggctgctgctggaggccgtggaatgac tctcttattccttggtgcttcttcgttgataatcatggttataacgttcaagacatgaca acaacaagtattggagttgaagccaaattaaacaggataccttcacctacactatttgga aatgacatcaacagtgttctcttcacaactcaaaatcagacacccaatcgtttccggttc aagattactgatccaaataatagaagatatgaagttcctcatcagtatgtaaaagagttt actggacccacagtttctgatacgttgtatgatgtgaaggttgcccaaaacccatttagc atccaagttattaggaaaagcaacggtaaaactttgtttgacaccagcattggtccctta gtgtactctgaccagtacttacagatctcaacccgtcttccaagtgattatatttatggt attggagaacaagttcataagagatttcgtcatgatttatcctggaaaacatggccaatt tttactcgagaccaacttcctggtgataataataataatttatacggccatcaaacattc tttatgtgtattgaagatacatctggaaagtcattcggtgtttttttaatgaatagcaat gcaatggagatttttatccagcctactccaatagtaacatatagagttaccggtggcatt ctggatttttacatccttctaggagatacaccagaacaagtagttcaacagtatcaacag cttgttggactaccagcaatgccagcatattggaatcttggattccaactaagtcgctgg aattataagtcactagatgtagtgaaagaagtggtaaggagaaaccgggaagctggcata ccatttgatacacaggtcactgatattgactacatggaagacaagaaagactttacttat gatcaagttgcgtttaacggactccctcaatttgtgcaagatttgcatgaccatggacag aaatatgtcatcatcttggaccctgcaatttccataggtcgacgtgccaatggaacaaca tatgcaacctatgagaggggaaacacacaacatgtgtggataaatgagtcagatggaagt acaccaattattggagaggtatggccaggattaacagtataccctgatttcactaaccca aactgcattgattggtgggcaaatgaatgcagtattttccatcaagaagtgcaatatgat ggactttggattgacatgaatgaagtttccagctttattcaaggttcaacaaaaggatgt aatgtaaacaaattgaattatccaccgtttactcctgatattcttgacaaactcatgtat tccaaaacaatttgcatggatgctgtgcagaactggggtaaacagtatgatgttcatagc ctctatggatacagcatggctatagccacagagcaagctgtacaaaaagtttttcctaat aagagaagcttcattcttacccgctcaacatttgctggatctggaagacatgctgcgcat tggttaggagacaatactgcttcatgggaacaaatggaatggtctataactggaatgctg gagttcagtttgtttggaatacctttggttggagcagacatctgtggatttgtggctgaa accacagaagaactttgcagaagatggatgcaacttggggcattttatccattttccaga aaccataattctgacggatatgaacatcaggatcctgcattttttgggcagaattcactt ttggttaaatcatcaaggcagtatttaactattcgctacaccttattacccttcctctac actctgttttataaagcccatgtgtttggagaaacagtagcaagaccagttcttcatgag ttttatgaggatacgaacagctggattgaggacactgagtttttgtggggccctgcatta cttattactcctgttctaaaacagggagcagatactgtgagtgcctacatccctgatgct atttggtatgattatgaatctggtgcaaaaaggccatggaggaaacaacgggttgatatg tatcttccagcagacaaaataggattacatcttagaggaggttatatcatccccattcaa gaaccagatgtaacaacaacagcaagccgtaagaatcctctaggacttatagtcgcatta ggtgaaaacaacacagccaaaggagactttttctgggatgatggagaaactaaagataca atacaaaatggcaactacatattatatacattttcagtttctaataacacattagatatt gtgtgcacacattcatcatatcaggaaggaactaccttagcatttcagactgtaaaaatc cttgggttgacagacagtgttacagaagttagagtggcggaaaataatcaaccaatgaac gctcattccaatttcacttatgatgcttctaaccaggttctcctaattgcagatctcaaa cttaatcttggaagaaactttagtgttcaatggaatcaaattttctcagaaaatgaaaga tttaattgttatccagatgcagatttggcaactgaacaaaagtgcacacaacgtggctgt gtatggagaacgggttcttctctatccaaagcacctgagtgttactttcccagacaagat aactcttattcagtcaactcagctcgctattcatccatgggtataacagctgacctccaa ctaaatactgcaaatgccagaataaagttaccttctgaccccatctcaactcttcgtgtg gaggtgaaatatcacaaaaatgatatgttgcagtttaagatttatgatccccaaaagaag agatatgaagtaccagtaccgttaaacattccaaccaccccaataagtacttatgaagac agactttatgatgtggaaatcaaggaaaatccttttggcatccagattcgacggagaagc agtggaagagtcatttgggattcttggctgcctggatttgcttttaatgaccagttcatt caaatatcgactcgcctgccatcagaatatatatatggttttggggaagtggaacataca gcatttaagcgagatctgaactggaatacttggggaatgttcacaagagaccaaccccct ggttacaaacttaattcctatggatttcatccctattacatggctctggaagaggagggc aatgctcatggtgttttcttactcaacagcaatgcaatggatgttacattccagccaact cctgctctaacttaccgtacagttggagggatcttggatttttatatgtttttgggccca actccagaagttgcaacaaagcaataccatgaagtaattggccatccagtcatgccagct tattgggctttgggattccaattatgtcgttatggatatgcaaatacttcagaggttcgg gaattatatgacgctatggtggctgctaacatcccctatgatgttcagtacacagacatt gactacatggaaaggcagctagactttacaattggtgaagcattccaggaccttcctcag tttgttgacaaaataagaggagaaggaatgagatacattattatcctggatccagcaatt tcaggaaatgaaacaaagacttaccctgcatttgaaagaggacagcagaatgatgtcttt gtcaaatggccaaacaccaatgacatttgttgggcaaaggtttggccagatttgcccaac ataacaatagataaaactctaacggaagatgaagctgttaatgcttccagagctcatgta gctttcccagatttcttcaggacttccacagcagagtggtgggccagagaaattgtggac ttttacaatgaaaagatgaagtttgatggtttgtggattgatatgaatgagccatcaagt tttgtaaatggaacaactactaatcaatgcagaaatgacgaactaaattatccaccttat ttcccagaactcacaaaaagaactgatggattacatttcagaacaatttgcatggaagct gagcagattcttagtgatggaacatcagttttgcattacgatgttcacaatctctatgga tggtcacagatgaaacctactcatgatgcattgcagaagacaactggaaaaagagggatt gtaatttctcgttccacgtatcctactagtggacgatggggaggacactggcttggagac aactatgcacgatgggacaacatggacaaatcaatcattggtatgatggaatttagtctg tttggaatgtcatatactggagcagacatctgtggttttttcaacaactcagaatatcat ctctgtacccgctggatgcaacttggagcattttatccatactcaaggaatcacaacatt gcaaatactagaagacaagatcccgcttcctggaatgaaacttttgctgaaatgtcaagg aatattctaaatattagatacaccttattgccctatttttacacacaaatgcatgaaatt catgctaatggtggcactgttatccgaccccttttgcatgagttctttgatgaaaaacca acctgggatatattcaagcagttcttatggggtccagcatttatggttaccccagtactg gaaccttatgttcaaactgtaaatgcctacgtccccaatgctcggtggtttgactaccat acaggcaaagatattggcgtcagaggacaatttcaaacatttaatgcttcttatgacaca ataaacctacatgtccgtggtggtcacatcctaccatgtcaagagccagctcaaaacaca ttttacagtcgacaaaaacacatgaagctcattgttgctgcagatgataatcagatggca cagggttctctgttttgggatgatggagagagtatagacacctatgaaagagacctatat ttatctgtacaatttaatttaaaccagaccaccttaacaagcactatattgaagagaggt tacataaataaaagtgaaacgaggcttggatcccttcatgtatgggggaaaggaactact cctgtcaatgcagttactctaacgtataacggaaataaaaattcgcttccttttaatgaa gacactaccaacatgatattacgtattgatctgaccacacacaatgttactctagaagaa ccaatagaaatcaactggtcatga

DBGET integrated database retrieval system