| Entry |
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| Symbol |
SCN9A, ETHA, FEB3B, GEFSP7, HSAN2D, NE-NA, NENA, Nav1.7, PN1, SFNP
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| Name |
(RefSeq) sodium voltage-gated channel alpha subunit 9
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| KO |
| K04841 | voltage-gated sodium channel type IX alpha |
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| Organism |
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| Pathway |
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| Disease |
| H00265 | Hereditary sensory and autonomic neuropathy |
| H00771 | Inherited erythromelalgia |
| H00772 | Paroxysmal extreme pain disorder |
| H00774 | Congenital insensitivity to pain |
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| Drug target |
| Ethyl piperidinoacetylaminobenzoate: | D01519 |
| Indecainide hydrochloride: | D04521 |
| Levosemotiadil fumarate: | D09833 |
| p-Butylaminobenzoyldiethylaminoethyl hydrochloride: | D01967 |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09157 Sensory system
04742 Taste transduction
6335 (SCN9A)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:hsa04040]
6335 (SCN9A)
Ion channels [BR:hsa04040]
Voltage-gated cation channels
Sodium channel, voltage-gated (Nav)
6335 (SCN9A)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
2:complement(166195185..166375987)
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| AA seq |
1977 aa
MAMLPPPGPQSFVHFTKQSLALIEQRIAERKSKEPKEEKKDDDEEAPKPSSDLEAGKQLP
FIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKTIFRFNATPALYMLSPFSPLRRISI
KILVHSLFSMLIMCTILTNCIFMTMNNPPDWTKNVEYTFTGIYTFESLVKILARGFCVGE
FTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQ
SVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFR
KYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQ
DYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKE
LEFQQMLDRLKKEQEEAEAIAAAAAEYTSIRRSRIMGLSESSSETSKLSSKSAKERRNRR
KKKNQKKLSSGEEKGDAEKLSKSESEDSIRRKSFHLGVEGHRRAHEKRLSTPNQSPLSIR
GSLFSARRSSRTSLFSFKGRGRDIGSETEFADDEHSIFGDNESRRGSLFVPHRPQERRSS
NISQASRSPPMLPVNGKMHSAVDCNGVVSLVDGRSALMLPNGQLLPEGTTNQIHKKRRCS
SYLLSEDMLNDPNLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHKFLIWNCSPYWI
KFKKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAAEM
VLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPT
LNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINDDCTLPRWHMN
DFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSF
SSDNLTAIEEDPDANNLQIAVTRIKKGINYVKQTLREFILKAFSKKPKISREIRQAEDLN
TKKENYISNHTLAEMSKGHNFLKEKDKISGFGSSVDKHLMEDSDGQSFIHNPSLTVTVPI
APGESDLENMNAEELSSDSDSEYSKVRLNRSSSSECSTVDNPLPGEGEEAEAEPMNSDEP
EACFTDGCVWRFSCCQVNIESGKGKIWWNIRKTCYKIVEHSWFESFIVLMILLSSGALAF
EDIYIERKKTIKIILEYADKIFTYIFILEMLLKWIAYGYKTYFTNAWCWLDFLIVDVSLV
TLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIF
WLIFSIMGVNLFAGKFYECINTTDGSRFPASQVPNRSECFALMNVSQNVRWKNLKVNFDN
VGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLNL
FIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKIQGCIFDL
VTNQAFDISIMVLICLNMVTMMVEKEGQSQHMTEVLYWINVVFIILFTGECVLKLISLRH
YYFTVGWNIFDFVVVIISIVGMFLADLIETYFVSPTLFRVIRLARIGRILRLVKGAKGIR
TLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEDGINDMFNFETFGNSMICL
FQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVV
VNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAAALDP
PLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSAN
PSKVSYEPITTTLKRKQEDVSATVIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLLNKKD
MAFDNVNENSSPEKTDATSSTTSPPSYDSVTKPDKEKYEQDRTEKEDKGKDSKESKK |
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| NT seq |
5934 nt +upstreamnt +downstreamnt
atggcaatgttgcctcccccaggacctcagagctttgtccatttcacaaaacagtctctt
gccctcattgaacaacgcattgctgaaagaaaatcaaaggaacccaaagaagaaaagaaa
gatgatgatgaagaagccccaaagccaagcagtgacttggaagctggcaaacagctgccc
ttcatctatggggacattcctcccggcatggtgtcagagcccctggaggacttggacccc
tactatgcagacaaaaagactttcatagtattgaacaaagggaaaacaatcttccgtttc
aatgccacacctgctttatatatgctttctcctttcagtcctctaagaagaatatctatt
aagattttagtacactccttattcagcatgctcatcatgtgcactattctgacaaactgc
atatttatgaccatgaataacccaccggactggaccaaaaatgtcgagtacacttttact
ggaatatatacttttgaatcacttgtaaaaatccttgcaagaggcttctgtgtaggagaa
ttcacttttcttcgtgacccgtggaactggctggattttgtcgtcattgtttttgcgtat
ttaacagaatttgtaaacctaggcaatgtttcagctcttcgaactttcagagtattgaga
gctttgaaaactatttctgtaatcccaggcctgaagacaattgtaggggctttgatccag
tcagtgaagaagctttctgatgtcatgatcctgactgtgttctgtctgagtgtgtttgca
ctaattggactacagctgttcatgggaaacctgaagcataaatgttttcgaaattcactt
gaaaataatgaaacattagaaagcataatgaataccctagagagtgaagaagactttaga
aaatatttttattacttggaaggatccaaagatgctctcctttgtggtttcagcacagat
tcaggtcagtgtccagaggggtacacctgtgtgaaaattggcagaaaccctgattatggc
tacacgagctttgacactttcagctgggccttcttagccttgtttaggctaatgacccaa
gattactgggaaaacctttaccaacagacgctgcgtgctgctggcaaaacctacatgatc
ttctttgtcgtagtgattttcctgggctccttttatctaataaacttgatcctggctgtg
gttgccatggcatatgaagaacagaaccaggcaaacattgaagaagctaaacagaaagaa
ttagaatttcaacagatgttagaccgtcttaaaaaagagcaagaagaagctgaggcaatt
gcagcggcagcggctgaatatacaagtattaggagaagcagaattatgggcctctcagag
agttcttctgaaacatccaaactgagctctaaaagtgctaaagaaagaagaaacagaaga
aagaaaaagaatcaaaagaagctctccagtggagaggaaaagggagatgctgagaaattg
tcgaaatcagaatcagaggacagcatcagaagaaaaagtttccaccttggtgtcgaaggg
cataggcgagcacatgaaaagaggttgtctacccccaatcagtcaccactcagcattcgt
ggctccttgttttctgcaaggcgaagcagcagaacaagtctttttagtttcaaaggcaga
ggaagagatataggatctgagactgaatttgccgatgatgagcacagcatttttggagac
aatgagagcagaaggggctcactgtttgtgccccacagaccccaggagcgacgcagcagt
aacatcagccaagccagtaggtccccaccaatgctgccggtgaacgggaaaatgcacagt
gctgtggactgcaacggtgtggtctccctggttgatggacgctcagccctcatgctcccc
aatggacagcttctgccagagggcacgaccaatcaaatacacaagaaaaggcgttgtagt
tcctatctcctttcagaggatatgctgaatgatcccaacctcagacagagagcaatgagt
agagcaagcatattaacaaacactgtggaagaacttgaagagtccagacaaaaatgtcca
ccttggtggtacagatttgcacacaaattcttgatctggaattgctctccatattggata
aaattcaaaaagtgtatctattttattgtaatggatccttttgtagatcttgcaattacc
atttgcatagttttaaacacattatttatggctatggaacaccacccaatgactgaggaa
ttcaaaaatgtacttgctataggaaatttggtctttactggaatctttgcagctgaaatg
gtattaaaactgattgccatggatccatatgagtatttccaagtaggctggaatattttt
gacagccttattgtgactttaagtttagtggagctctttctagcagatgtggaaggattg
tcagttctgcgatcattcagactgctccgagtcttcaagttggcaaaatcctggccaaca
ttgaacatgctgattaagatcattggtaactcagtaggggctctaggtaacctcacctta
gtgttggccatcatcgtcttcatttttgctgtggtcggcatgcagctctttggtaagagc
tacaaagaatgtgtctgcaagatcaatgatgactgtacgctcccacggtggcacatgaac
gacttcttccactccttcctgattgtgttccgcgtgctgtgtggagagtggatagagacc
atgtgggactgtatggaggtcgctggtcaagctatgtgccttattgtttacatgatggtc
atggtcattggaaacctggtggtcctaaacctatttctggccttattattgagctcattt
agttcagacaatcttacagcaattgaagaagaccctgatgcaaacaacctccagattgca
gtgactagaattaaaaagggaataaattatgtgaaacaaaccttacgtgaatttattcta
aaagcattttccaaaaagccaaagatttccagggagataagacaagcagaagatctgaat
actaagaaggaaaactatatttctaaccatacacttgctgaaatgagcaaaggtcacaat
ttcctcaaggaaaaagataaaatcagtggttttggaagcagcgtggacaaacacttgatg
gaagacagtgatggtcaatcatttattcacaatcccagcctcacagtgacagtgccaatt
gcacctggggaatccgatttggaaaatatgaatgctgaggaacttagcagtgattcggat
agtgaatacagcaaagtgagattaaaccggtcaagctcctcagagtgcagcacagttgat
aaccctttgcctggagaaggagaagaagcagaggctgaacctatgaattccgatgagcca
gaggcctgtttcacagatggttgtgtatggaggttctcatgctgccaagttaacatagag
tcagggaaaggaaaaatctggtggaacatcaggaaaacctgctacaagattgttgaacac
agttggtttgaaagcttcattgtcctcatgatcctgctcagcagtggtgccctggctttt
gaagatatttatattgaaaggaaaaagaccattaagattatcctggagtatgcagacaag
atcttcacttacatcttcattctggaaatgcttctaaaatggatagcatatggttataaa
acatatttcaccaatgcctggtgttggctggatttcctaattgttgatgtttctttggtt
actttagtggcaaacactcttggctactcagatcttggccccattaaatcccttcggaca
ctgagagctttaagacctctaagagccttatctagatttgaaggaatgagggtcgttgtg
aatgcactcataggagcaattccttccatcatgaatgtgctacttgtgtgtcttatattc
tggctgatattcagcatcatgggagtaaatttgtttgctggcaagttctatgagtgtatt
aacaccacagatgggtcacggtttcctgcaagtcaagttccaaatcgttccgaatgtttt
gcccttatgaatgttagtcaaaatgtgcgatggaaaaacctgaaagtgaactttgataat
gtcggacttggttacctatctctgcttcaagttgcaacttttaagggatggacgattatt
atgtatgcagcagtggattctgttaatgtagacaagcagcccaaatatgaatatagcctc
tacatgtatatttattttgtcgtctttatcatctttgggtcattcttcactttgaacttg
ttcattggtgtcatcatagataatttcaaccaacagaaaaagaagcttggaggtcaagac
atctttatgacagaagaacagaagaaatactataatgcaatgaaaaagctggggtccaag
aagccacaaaagccaattcctcgaccagggaacaaaatccaaggatgtatatttgaccta
gtgacaaatcaagcctttgatattagtatcatggttcttatctgtctcaacatggtaacc
atgatggtagaaaaggagggtcaaagtcaacatatgactgaagttttatattggataaat
gtggtttttataatccttttcactggagaatgtgtgctaaaactgatctccctcagacac
tactacttcactgtaggatggaatatttttgattttgtggttgtgattatctccattgta
ggtatgtttctagctgatttgattgaaacgtattttgtgtcccctaccctgttccgagtg
atccgtcttgccaggattggccgaatcctacgtctagtcaaaggagcaaaggggatccgc
acgctgctctttgctttgatgatgtcccttcctgcgttgtttaacatcggcctcctgctc
ttcctggtcatgttcatctacgccatctttggaatgtccaactttgcctatgttaaaaag
gaagatggaattaatgacatgttcaattttgagacctttggcaacagtatgatttgcctg
ttccaaattacaacctctgctggctgggatggattgctagcacctattcttaacagtaag
ccacccgactgtgacccaaaaaaagttcatcctggaagttcagttgaaggagactgtggt
aacccatctgttggaatattctactttgttagttatatcatcatatccttcctggttgtg
gtgaacatgtacattgcagtcatactggagaattttagtgttgccactgaagaaagtact
gaacctctgagtgaggatgactttgagatgttctatgaggtttgggagaagtttgatccc
gatgcgacccagtttatagagttctctaaactctctgattttgcagctgccctggatcct
cctcttctcatagcaaaacccaacaaagtccagctcattgccatggatctgcccatggtt
agtggtgaccggatccattgtcttgacatcttatttgcttttacaaagcgtgttttgggt
gagagtggggagatggattctcttcgttcacagatggaagaaaggttcatgtctgcaaat
ccttccaaagtgtcctatgaacccatcacaaccacactaaaacggaaacaagaggatgtg
tctgctactgtcattcagcgtgcttatagacgttaccgcttaaggcaaaatgtcaaaaat
atatcaagtatatacataaaagatggagacagagatgatgatttactcaataaaaaagat
atggcttttgataatgttaatgagaactcaagtccagaaaaaacagatgccacttcatcc
accacctctccaccttcatatgatagtgtaacaaagccagacaaagagaaatatgaacaa
gacagaacagaaaaggaagacaaagggaaagacagcaaggaaagcaaaaaatag |
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