Address
:
[go:
up one dir
,
main page
]
Include Form
Remove Scripts
Accept Cookies
Show Images
Show Referer
Rotate13
Base64
Strip Meta
Strip Title
Session Cookies
Homo sapiens (human): 5745
Help
Entry
5745 CDS
T01001
Symbol
PTH1R, EKNS, PFE, PTHR, PTHR1
Name
(RefSeq) parathyroid hormone 1 receptor
KO
K04585
parathyroid hormone receptor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa04961
Endocrine and other factor-regulated calcium reabsorption
Network
nt06318
CaSR-PTH signaling
Element
N00288
PTH-PTH1R-PKA signaling pathway
Disease
H00479
Metaphyseal dysplasias
H00495
Eiken dysplasia
H00508
Blomstrand syndrome
H00680
Primary failure of tooth eruption
Drug target
Abaloparatide (
DG03050
):
D10885
<US>
D11563
<JP>
Eneboparatide:
D12805
Palopegteriparatide:
D12395
<US>
Parathyroid hormone:
D05364
<US>
Teriparatide (
DG00512
):
D03358
<JP>
D06078
<JP/US>
D06546
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
5745 (PTH1R)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
5745 (PTH1R)
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
5745 (PTH1R)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
5745 (PTH1R)
G protein-coupled receptors [BR:
hsa04030
]
Secretin receptor family
Calcium-regulating peptide
Parathyroid hormone
5745 (PTH1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_2
HRM
Motif
Other DBs
NCBI-GeneID:
5745
NCBI-ProteinID:
NP_000307
OMIM:
168468
HGNC:
9608
Ensembl:
ENSG00000160801
UniProt:
Q03431
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:46877721..46903799
Genome browser
AA seq
593 aa
AA seq
DB search
MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA
SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL
GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE
REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK
DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL
VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK
WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH
YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA
LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP
GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atggggaccgcccggatcgcacccggcctggcgctcctgctctgctgccccgtgctcagc
tccgcgtacgcgctggtggatgcagatgacgtcatgactaaagaggaacagatcttcctg
ctgcaccgtgctcaggcccagtgcgaaaaacggctcaaggaggtcctgcagaggccagcc
agcataatggaatcagacaagggatggacatctgcgtccacatcagggaagcccaggaaa
gataaggcatctgggaagctctaccctgagtctgaggaggacaaggaggcacccactggc
agcaggtaccgagggcgcccctgtctgccggaatgggaccacatcctgtgctggccgctg
ggggcaccaggtgaggtggtggctgtgccctgtccggactacatttatgacttcaatcac
aaaggccatgcctaccgacgctgtgaccgcaatggcagctgggagctggtgcctgggcac
aacaggacgtgggccaactacagcgagtgtgtcaaatttctcaccaatgagactcgtgaa
cgggaggtgtttgaccgcctgggcatgatttacaccgtgggctactccgtgtccctggcg
tccctcaccgtagctgtgctcatcctggcctactttaggcggctgcactgcacgcgcaac
tacatccacatgcacctgttcctgtccttcatgctgcgcgccgtgagcatcttcgtcaag
gacgctgtgctctactctggcgccacgcttgatgaggctgagcgcctcaccgaggaggag
ctgcgcgccatcgcccaggcgcccccgccgcctgccaccgccgctgccggctacgcgggc
tgcagggtggctgtgaccttcttcctttacttcctggccaccaactactactggattctg
gtggaggggctgtacctgcacagcctcatcttcatggccttcttctcagagaagaagtac
ctgtggggcttcacagtcttcggctggggtctgcccgctgtcttcgtggctgtgtgggtc
agtgtcagagctaccctggccaacaccgggtgctgggacttgagctccgggaacaaaaag
tggatcatccaggtgcccatcctggcctccattgtgctcaacttcatcctcttcatcaat
atcgtccgggtgctcgccaccaagctgcgggagaccaacgccggccggtgtgacacacgg
cagcagtaccggaagctgctcaaatccacgctggtgctcatgcccctctttggcgtccac
tacattgtcttcatggccacaccatacaccgaggtctcagggacgctctggcaagtccag
atgcactatgagatgctcttcaactccttccagggattttttgtcgcaatcatatactgt
ttctgcaatggcgaggtacaagctgagatcaagaaatcttggagccgctggacactggca
ctggacttcaagcgaaaggcacgcagcgggagcagcagctatagctacggccccatggtg
tcccacacaagtgtgaccaatgtcggcccccgtgtgggactcggcctgcccctcagcccc
cgcctactgcccactgccaccaccaacggccaccctcagctgcctggccatgccaagcca
gggaccccagccctggagaccctcgagaccacaccacctgccatggctgctcccaaggac
gatgggttcctcaacggctcctgctcaggcctggacgaggaggcctctgggcctgagcgg
ccacctgccctgctacaggaagagtgggagacagtcatgtga
DBGET
integrated database retrieval system