Homo sapiens (human): 4049 Help Entry 4049              CDS       T01001                                  Symbol LTA, LT, TNFB, TNFSF1, TNLG1E Name (RefSeq) lymphotoxin alpha   KO K05468   lymphotoxin alpha (TNF superfamily, member 1) Organism hsa  Homo sapiens (human) Pathway hsa04060   Cytokine-cytokine receptor interaction hsa04061   Viral protein interaction with cytokine and cytokine receptor hsa04064   NF-kappa B signaling pathway hsa04668   TNF signaling pathway hsa04940   Type I diabetes mellitus hsa05166   Human T-cell leukemia virus 1 infection hsa05168   Herpes simplex virus 1 infection Disease H00344   Leprosy H01730   Myocardial infarction Drug target Etanercept:  D00742<JP/US> Lenercept:  D04690 Pateclizumab:  D10187 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     4049 (LTA)    04668 TNF signaling pathway     4049 (LTA)   09133 Signaling molecules and interaction    04061 Viral protein interaction with cytokine and cytokine receptor     4049 (LTA)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     4049 (LTA)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     4049 (LTA)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:hsa04052]     4049 (LTA) Cytokines and neuropeptides [BR:hsa04052]  Cytokines   Tumor necrosis fators    4049 (LTA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  4049 NCBI-ProteinID:  NP_000586 OMIM:  153440 HGNC:  6709 Ensembl:  ENSG00000226979 UniProt:  P01374 Q5STV3 Structure PDBPDBj LinkDB All DBs Position 6:31560610..31574324 Genome browser AA seq 205 aa AA seqDB search MTPPERLFLPRVCGTTLHLLLLGLLLVLLPGAQGLPGVGLTPSAAQTARQHPKMHLAHST LKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAY SPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQ LSTHTDGIPHLVLSPSTVFFGAFAL NT seq 618 nt NT seq  +upstreamnt  +downstreamnt atgacaccacctgaacgtctcttcctcccaagggtgtgtggcaccaccctacacctcctc cttctggggctgctgctggttctgctgcctggggcccaggggctccctggtgttggcctc acaccttcagctgcccagactgcccgtcagcaccccaagatgcatcttgcccacagcacc ctcaaacctgctgctcacctcattggagaccccagcaagcagaactcactgctctggaga gcaaacacggaccgtgccttcctccaggatggtttctccttgagcaacaattctctcctg gtccccaccagtggcatctacttcgtctactcccaggtggtcttctctgggaaagcctac tctcccaaggccacctcctccccactctacctggcccatgaggtccagctcttctcctcc cagtaccccttccatgtgcctctcctcagctcccagaagatggtgtatccagggctgcag gaaccctggctgcactcgatgtaccacggggctgcgttccagctcacccagggagaccag ctatccacccacacagatggcatcccccacctagtcctcagccctagtactgtcttcttt ggagccttcgctctgtag

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