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KEGG   REACTION: R12497
Entry
R12497                      Reaction                               
Name
S-adenosyl-L-methionine:cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} C-methyltransferase
Definition
2 S-Adenosyl-L-methionine + Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Reduced acceptor <=> S-Adenosyl-L-homocysteine + 5'-Deoxyadenosine + L-Methionine + Cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + Acceptor
Equation
Comment
three-step reaction (see R13182+R13410+R13183)
Reaction class
RC02370  C22216_C22217
Enzyme
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.308
     R12497  2 S-Adenosyl-L-methionine + Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + Reduced acceptor <=> S-Adenosyl-L-homocysteine + 5'-Deoxyadenosine + L-Methionine + Cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + Acceptor
Orthology
K12902  phosphonoacetaldehyde methylase [EC:2.1.1.308]
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