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KEGG   REACTION: R00980
Entry
R00980                      Reaction                               
Name
anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating)
Definition
Anthranilate + Oxygen + NADPH + H+ <=> 2,3-Dihydroxybenzoate + Ammonia + NADP+
Equation
C00108 + C00007 + C00005 + C00080 <=> C00196 + C00014 + C00006
Comment
the oxygen atom at the 3-position of the product, 2,3-
dihydroxybenzoate, originates from O2, while that at the 2-position
is derived from H2O.
Reaction class
RC00001  C00005_C00006
RC00412  C00108_C00196
Enzyme
1.14.13.35
Pathway
rn00627  Aminobenzoate degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.35
     R00980  Anthranilate + Oxygen + NADPH + H+ <=> 2,3-Dihydroxybenzoate + Ammonia + NADP+
Reference
1  [PMID:3793735]
  Authors
Powlowski JB, Dagley S, Massey V, Ballou DP.
  Title
Properties of anthranilate hydroxylase (deaminating), a flavoprotein from Trichosporon cutaneum.
  Journal
J Biol Chem 262:69-74 (1987)
Other DBs
RHEA: 21239
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