[go: up one dir, main page]

KEGG   NETWORK: N01520
Entry
N01520                      Network                                
Name
Regulation of fibrinolytic system, C1INH
Definition
SERPING1 -| (F11a,F12a,Kallikrein,Plasmin,PLAU,C1R,C1S,MASP1/2)
  Expanded
710 -| (C03262,C03379,C01715,C00471,5328,715,716,(5648,10747))
Class
nt06513 Complement cascade
nt06514 Coagulation cascade
Type
Reference
Pathway
hsa04610  Complement and coagulation cascades
Gene
710  SERPING1; serpin family G member 1
5328  PLAU; plasminogen activator, urokinase
715  C1R; complement C1r
716  C1S; complement C1s
5648  MASP1; MBL associated serine protease 1
10747  MASP2; MBL associated serine protease 2
Metabolite
C03262  Coagulation factor XIa
C03379  Coagulation factor XIIa
C01715  Plasma kallikrein
C00471  Plasmin
Reference
  Authors
Levi M, Cohn DM, Zeerleder S
  Title
Hereditary angioedema: Linking complement regulation to the coagulation system.
  Journal
Res Pract Thromb Haemost 3:38-43 (2019)
DOI:10.1002/rth2.12175
Reference
  Authors
Yaron JR, Zhang L, Guo Q, Haydel SE, Lucas AR
  Title
Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms.
  Journal
Front Cardiovasc Med 8:648947 (2021)
DOI:10.3389/fcvm.2021.648947
LinkDB

DBGET integrated database retrieval system