| Entry |
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| Name |
Chlorpheniramine polistirex and codeine polistirex;
Tuzistra (TN) |
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| Component |
Chlorpheniramine polistirex [DR: D03475], Codeine polistirex [DR: D03579]
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| Class |
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| Remark |
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| Efficacy |
Antitussive |
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| Comment |
Codeine is metabolized by UGT2B7, UGT2B4, CYP3A4 and CYP2D6.
Chlorpheniramine is metabolized by CYP2D6.
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| Metabolism |
Enzyme: UGT2B7 [HSA: 7364], UGT2B4 [HSA: 7363], CYP3A4 [HSA: 1576], CYP2D6 [HSA: 1565]
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB54 Chlorphenamine, combinations
D12313 Chlorpheniramine polistirex and codeine polistirex
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
D12313 Chlorpheniramine polistirex and codeine polistirex
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D12313 Chlorpheniramine polistirex and codeine polistirex
DG02924 UGT substrate
DG03189 UGT2B4 substrate
D12313 Chlorpheniramine polistirex and codeine polistirex
DG03190 UGT2B7 substrate
D12313 Chlorpheniramine polistirex and codeine polistirex
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D12313
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| Other DBs |
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| LinkDB |
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