KEGG DRUG: Cenegermin

DRUG: Cenegermin

Entry

D11028                      Drug

Name

Cenegermin (INN);
Cenegermin-bkbj;
Oxervate (TN)

Product

OXERVATE (Dompé farmaceutici S.p.A.)

Sequence

SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD
PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR
(Disulfide bridge: 15-80, 58-108, 68-110)

Type

Peptide

Remark

ATC code:

S01XA24

Product:

D11028<US>

Efficacy

Antiglaucoma, Neuroprotectant

Comment

recombinant human nerve growth factor [HSA:4803] [KO:K02582]
Treatment of moderate to severe neurotrophic keratitis

Target

NGFR (TNFRSF16, CD271) [HSA:4804] [KO:K02583]

Pathway

hsa04060

Cytokine-cytokine receptor interaction

hsa04722

Neurotrophin signaling pathway

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01X OTHER OPHTHALMOLOGICALS
    S01XA Other ophthalmologicals
     S01XA24 Cenegermin
      D11028  Cenegermin (INN) <US>
USP drug classification [BR:br08302]
Ophthalmic Agents
  Ophthalmic Agents, Other
   Cenegermin
    D11028  Cenegermin (INN)
Target-based classification of drugs [BR:br08310]
Cytokines and receptors
  Cytokine receptors
   Tumor necrosis factor receptors
    NGFR (TNFRSF16, CD271)
     D11028  Cenegermin (INN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
  D11028
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
  D11028
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
  D11028

Other DBs

CAS:	1772578-74-1

PubChem:

350078347

LinkDB

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