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KEGG   DRUG: Dienogest and estradiol valerate
Entry
D10461            Mixture   Drug                                   
Name
Dienogest and estradiol valerate;
Natazia (TN)
Product
  Generic
Component
Dienogest [DR:D03799], Estradiol valerate [DR:D01413]
Class
Metabolizing enzyme substrate
 DG01633  CYP3A/CYP3A4 substrate
Remark
ATC code: G03AB08
Product: D10461<US>
Efficacy
Contraceptive
Comment
Combination of estrogen and progestin
Metabolism
Enzyme: CYP3A [HSA:1576 1577 1551]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
    G03AB Progestogens and estrogens, sequential preparations
     G03AB08 Dienogest and estradiol
      D10461  Dienogest and estradiol valerate <US>
USP drug classification [BR:br08302]
 Contraceptives
  Oral Contraceptives Combinations
   Dienogest/ Estradiol Valerate
    D10461  Dienogest and estradiol valerate
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   D10461  Dienogest and estradiol valerate
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10461
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10461
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D10461
Other DBs
PubChem: 172232554
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