Entry |
|
Name |
Azilsartan medoxomil (USAN) |
Formula |
C30H24N4O8
|
Exact mass |
568.1594
|
Mol weight |
568.53
|
Structure |
|
Simcomp |
|
Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01495 Angiotensin II receptor antagonist
DG03231 Antihypertensive
DG01495 Angiotensin II receptor antagonist
|
Remark |
Product (DG00351): | D08864<JP> D08865<US> |
Product (mixture): | D10589<US> |
|
Efficacy |
Antihypertensive, Angiotensin II receptor antagonist |
Disease |
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
hsa04261 | Adrenergic signaling in cardiomyocytes |
hsa04270 | Vascular smooth muscle contraction |
|
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN
C09CA Angiotensin II receptor blockers (ARBs), plain
C09CA09 Azilsartan medoxomil
D08067 Azilsartan medoxomil (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01495 Angiotensin II receptor antagonist
DG00351 Azilsartan
D08067 Azilsartan medoxomil
DG03231 Antihypertensive
DG01495 Angiotensin II receptor antagonist
DG00351 Azilsartan
D08067 Azilsartan medoxomil
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Angiotensin
AGTR1
D08067 Azilsartan medoxomil (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01495 Angiotensin II receptor antagonist
DG00351 Azilsartan
DG03231 Antihypertensive
DG01495 Angiotensin II receptor antagonist
DG00351 Azilsartan
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 42
1 C8y C 28.7000 -21.1400
2 N4y N 28.2800 -19.8100
3 C8y C 30.1000 -21.1400
4 C8y C 28.0000 -22.3300
5 C8y C 29.4000 -18.9700
6 C1b C 27.0900 -19.1100
7 N5x N 30.5900 -19.8100
8 C8x C 30.8000 -22.3300
9 C8x C 28.7000 -23.5200
10 C7a C 27.3000 -23.5200
11 O2a O 29.4000 -17.5700
12 C8y C 25.9000 -19.8100
13 C8x C 30.1000 -23.5200
14 O6a O 28.0000 -24.7800
15 C1b C 30.6600 -16.8700
16 C8x C 24.6400 -19.1800
17 C8x C 25.9000 -21.2100
18 C1a C 30.6600 -15.4700
19 C8x C 23.4500 -19.8800
20 C8x C 24.7100 -21.9800
21 C8y C 23.4500 -21.2800
22 C8y C 22.2600 -21.9800
23 C8y C 21.0000 -21.3500
24 C8x C 22.2600 -23.3800
25 C8y C 21.0000 -19.8800
26 C8x C 19.8100 -22.0500
27 C8x C 21.0700 -24.1500
28 N4x N 19.8800 -19.1100
29 N5x N 22.1200 -19.0400
30 C8x C 19.8100 -23.4500
31 C8y C 20.3000 -17.7800
32 O7x O 21.7000 -17.7800
33 O6a O 19.3900 -16.6600
34 O7a O 25.9000 -23.5200
35 C1b C 25.2000 -24.7324
36 C8y C 25.8904 -25.9279
37 C8y C 25.4778 -27.2348
38 O7x O 26.5915 -28.0338
39 C8y C 27.6955 -27.2215
40 O7x O 27.2641 -25.9206
41 C1a C 24.1529 -27.6759
42 O6a O 29.0543 -27.6540
BOND 47
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 4 10 1
10 5 11 1
11 6 12 1
12 8 13 2
13 10 14 2
14 11 15 1
15 12 16 1
16 12 17 2
17 15 18 1
18 16 19 2
19 17 20 1
20 19 21 1
21 21 22 1
22 22 23 1
23 22 24 2
24 23 25 1
25 23 26 2
26 24 27 1
27 25 28 1
28 25 29 2
29 26 30 1
30 28 31 1
31 29 32 1
32 5 7 2
33 9 13 1
34 20 21 2
35 27 30 2
36 31 32 1
37 31 33 2
38 10 34 1
39 34 35 1
40 35 36 1
41 36 37 2
42 37 38 1
43 38 39 1
44 39 40 1
45 36 40 1
46 37 41 1
47 39 42 2
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