KEGG DRUG: Prasterone

DRUG: Prasterone

Entry

D08409                      Drug

Name

Prasterone (USAN/INN);
Biolaif (TN)

Product

INTRAROSA (Millicent US)

Formula

C19H28O2

Exact mass

288.2089

Mol weight

288.42

Structure

Simcomp

Class

Hormonal agent
DG01590 Androgen receptor agonist
DG01605 Anabolic steroid

Remark

Same as:

C01227

ATC code:

A14AA07 G03XX01

Chemical structure group:

DG00141

Product (DG00141):

D08409<US>

Efficacy

Accelerator (cervical ripening), Androgen receptor agonist

Comment

Androstan derivative

Target

NR3C4 (AR) [HSA:367] [KO:K08557]
NR3A (ESR) [HSA:2099 2100] [KO:K08550 K08551]

Pathway

hsa04915

Estrogen signaling pathway

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
  A14 ANABOLIC AGENTS FOR SYSTEMIC USE
   A14A ANABOLIC STEROIDS
    A14AA Androstan derivatives
     A14AA07 Prasterone
      D08409  Prasterone (USAN/INN) <US>
G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03X OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
    G03XX Other sex hormones and modulators of the genital system
     G03XX01 Prasterone
      D08409  Prasterone (USAN/INN) <US>
USP drug classification [BR:br08302]
Sexual Disorder Agents
  Sexual Disorder Agents (Female)
   Prasterone
    D08409  Prasterone (USAN/INN)
Drug groups [BR:br08330]
Hormonal agent
  DG01590  Androgen receptor agonist
   DG01605  Anabolic steroid
    DG00141  Prasterone
     D08409  Prasterone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
  Estrogen like receptors
   Estrogen receptor
    NR3A (ESR)
     D08409  Prasterone (USAN/INN) <US>
   3-Ketosteroid receptor
    NR3C4 (AR)
     D08409  Prasterone (USAN/INN) <US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
  D08409
Drug groups [BR:br08330]
Hormonal agent
  DG01590  Androgen receptor agonist
   DG01605  Anabolic steroid
    DG00141  Prasterone

Other DBs

CAS:

53-43-0

PubChem:

96025095

ChEBI:

28689

PDB-CCD:

AND[PDBj]

LigandBox:

D08409

NIKKAJI:

J4.147E

LinkDB

KCF data

ATOM        21
            1   C1y C    25.3400  -18.9700
            2   C1y C    24.1500  -18.3400
            3   C1y C    26.4600  -18.2700
            4   C1x C    25.3400  -20.3700
            5   C1z C    22.9600  -18.9700
            6   C1x C    24.1500  -16.9400
            7   C1z C    26.5300  -16.9400
            8   C1x C    28.8400  -18.2700
            9   C2x C    24.1500  -21.0000
            10  C2y C    22.9600  -20.3000
            11  C1x C    21.8400  -18.3400
            12  C1a C    23.0300  -17.5000
            13  C1x C    25.3400  -16.2400
            14  C5x C    27.6500  -16.2400
            15  C1a C    26.5300  -15.2600
            16  C1x C    28.8400  -16.9400
            17  C1x C    21.8400  -21.0000
            18  C1x C    20.6500  -18.9700
            19  O5x O    27.6500  -14.9100
            20  C1y C    20.6500  -20.3000
            21  O1a O    19.5300  -21.0000
BOND        24
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 1
            11    5  12 1 #Up
            12    6  13 1
            13    7  14 1
            14    7  15 1 #Up
            15    8  16 1
            16   10  17 1
            17   11  18 1
            18   14  19 2
            19   17  20 1
            20   20  21 1 #Up
            21    7  13 1
            22    9  10 2
            23   14  16 1
            24   18  20 1

» Japanese version » Back

DBGET integrated database retrieval system