| Entry |
|
|---|
| Name |
Epanolol (USAN/INN) |
|---|
| Formula |
C20H23N3O4
|
|---|
| Exact mass |
369.1689
|
|---|
| Mol weight |
369.41
|
|---|
| Structure |
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Vasodilator, beta1-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AB Beta blocking agents, selective
C07AB10 Epanolol
D06646 Epanolol (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
D06646 Epanolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
D06646 Epanolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D06646 Epanolol (USAN/INN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C8x C 24.5000 -20.2300
2 C8x C 24.5000 -18.7600
3 C8x C 23.2400 -20.9300
4 C8y C 23.2400 -18.0600
5 C8x C 22.0500 -20.1600
6 C8y C 22.0500 -18.7600
7 C3b C 20.8600 -18.0600
8 N3a N 19.6000 -17.4300
9 O2a O 23.2400 -16.6600
10 C1b C 24.5000 -15.9600
11 C1c C 25.6900 -16.6600
12 C1b C 26.8800 -15.9600
13 N1b N 28.1400 -16.6600
14 C1b C 29.3300 -16.0300
15 C1b C 30.5200 -16.7300
16 N1b N 31.7800 -16.0300
17 C5a C 32.9700 -16.7300
18 O5a O 34.1600 -16.0300
19 C1b C 32.9700 -18.1300
20 C8y C 31.7800 -18.8300
21 C8x C 30.5200 -18.0600
22 C8x C 29.3300 -18.7600
23 C8y C 29.3300 -20.1600
24 C8x C 30.5200 -20.8600
25 C8x C 31.7800 -20.1600
26 O1a O 28.1400 -20.8600
27 O1a O 25.6900 -18.0600
BOND 28
1 4 6 1
2 13 14 1
3 6 7 1
4 14 15 1
5 7 8 3
6 15 16 1
7 5 6 2
8 16 17 1
9 17 18 2
10 4 9 1
11 17 19 1
12 1 2 1
13 19 20 1
14 9 10 1
15 1 3 2
16 10 11 1
17 2 4 2
18 11 12 1
19 20 21 2
20 21 22 1
21 22 23 2
22 23 24 1
23 24 25 2
24 25 20 1
25 3 5 1
26 23 26 1
27 12 13 1
28 27 11 1
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