| Entry |
|
|---|
| Name |
Elarofiban (USAN) |
|---|
| Formula |
C22H32N4O4. H2O
|
|---|
| Exact mass |
434.2529
|
|---|
| Mol weight |
434.53
|
|---|
| Structure |
|
|---|
| Class |
Blood modifier agent
DG01811 Fibrinogen receptor antagonist
|
|---|
| Efficacy |
Platelet aggregation inhibitor, Glycoprotein IIb/IIIa receptor antagonist |
|---|
| Comment |
Treatment of thrombotic disorders
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Drug groups [BR:br08330]
Blood modifier agent
DG01811 Fibrinogen receptor antagonist
D03971 Elarofiban
Target-based classification of drugs [BR:br08310]
Cell surface molecules and ligands
Cell adhesion molecules: other families
Integrins
ITGA2B/ITGB3
D03971 Elarofiban (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 C1x C 9.8000 -16.2400
2 N1x N 9.8000 -17.6400
3 C1x C 11.0124 -18.3400
4 C1x C 12.2249 -17.6400
5 C1y C 12.2249 -16.2400
6 C1x C 11.0124 -15.5400
7 C1b C 13.4560 -15.5290
8 C1b C 14.6612 -16.2247
9 C5a C 15.8435 -15.5419
10 N1y N 17.0375 -16.2312
11 O5a O 15.8435 -14.1402
12 C1x C 17.0376 -17.6397
13 C1x C 18.2501 -18.3396
14 C1x C 19.4625 -17.6395
15 C1y C 19.4623 -16.2309
16 C1x C 18.2498 -15.5311
17 C5a C 20.6690 -15.5341
18 N1b N 21.8697 -16.2273
19 O5a O 20.6689 -14.1401
20 C1c C 23.0543 -15.5433
21 C1b C 24.2470 -16.2320
22 C6a C 25.4357 -15.5457
23 C8y C 23.0544 -14.1402
24 C8x C 24.2485 -13.4506
25 N5x N 24.2484 -12.0506
26 C8x C 23.0359 -11.3507
27 C8x C 21.8417 -12.0403
28 C8x C 21.8419 -13.4403
29 O6a O 26.6263 -16.2332
30 O6a O 25.4358 -14.1402
31 O0 O 24.2900 -19.0400
BOND 32
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 9 11 2
12 10 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 10 16 1
18 15 17 1 #Down
19 17 18 1
20 17 19 2
21 18 20 1
22 20 21 1
23 21 22 1
24 20 23 1 #Down
25 23 24 2
26 24 25 1
27 25 26 2
28 26 27 1
29 27 28 2
30 23 28 1
31 22 29 1
32 22 30 2
|
|---|