| Entry |
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| Name |
Levocabastine hydrochloride (JAN/USP);
Livostin (TN) |
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| Formula |
C26H29FN2O2. HCl
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| Exact mass |
456.1980
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| Mol weight |
456.98
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| Structure |
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| Simcomp |
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
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| Remark |
| Product (DG01035): | D01717<JP> |
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| Efficacy |
Antiallergic, H1 receptor antagonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AC Antiallergic agents, excl. corticosteroids
R01AC02 Levocabastine
D01717 Levocabastine hydrochloride (JAN/USP) <JP>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GX Other antiallergics
S01GX02 Levocabastine
D01717 Levocabastine hydrochloride (JAN/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D01717 Levocabastine hydrochloride (JAN/USP)
132 Otic and nasal agents
1329 Others
D01717 Levocabastine hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01035 Levocabastine
D01717 Levocabastine hydrochloride
Drug classes [BR:br08332]
Anti-allergic agent
DG01482 Histamine receptor H1 antagonist
D01717 Levocabastine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D01717 Levocabastine hydrochloride (JAN/USP) <JP>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D01717
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01035 Levocabastine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 32
1 C8y C 21.0420 -18.8054
2 C8x C 19.6403 -18.8054
3 C8x C 18.9359 -20.0202
4 C8y C 19.6403 -21.2280
5 C8x C 21.0420 -21.2280
6 C8x C 21.7394 -20.0202
7 C8y C 30.4521 -18.8733
8 C8x C 29.7479 -20.0846
9 C8x C 30.4388 -21.2968
10 C8x C 31.8410 -21.3045
11 C8x C 32.5525 -20.1001
12 C8x C 31.8545 -18.8810
13 C1z C 22.2604 -18.1081
14 C1x C 22.9507 -19.3662
15 C1x C 24.3461 -19.3941
16 C1y C 25.0511 -18.1169
17 C1x C 24.3538 -16.8353
18 C1x C 22.9585 -16.9009
19 N1y N 26.4481 -18.1160
20 C1x C 27.1415 -19.3332
21 C1x C 28.5431 -19.3375
22 C1z C 29.2514 -18.1717
23 C1y C 28.5509 -16.8378
24 C1x C 27.1491 -16.9034
25 C6a C 30.4521 -17.4644
26 C3b C 21.0420 -17.4107
27 O6a O 31.1495 -16.2458
28 O6a O 31.8046 -17.8236
29 X F 18.9289 -22.4329
30 N3a N 19.8233 -16.7064
31 C1a C 29.2354 -15.6437
32 X Cl 25.2751 -21.9960
BOND 34
1 13 14 1
2 14 15 1
3 15 16 1
4 16 17 1
5 17 18 1
6 18 13 1
7 5 6 2
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 19 20 1
14 20 21 1
15 21 22 1
16 22 23 1
17 23 24 1
18 24 19 1
19 16 19 1 #Up
20 12 7 1
21 22 25 1 #Down
22 6 1 1
23 13 26 1 #Up
24 13 1 1 #Down
25 22 7 1 #Up
26 1 2 2
27 25 27 2
28 2 3 1
29 25 28 1
30 3 4 2
31 4 29 1
32 4 5 1
33 26 30 3
34 23 31 1 #Up
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