| Entry |
|
|---|
| Name |
Ifenprodil tartrate (JP18);
Cerocral (TN) |
|---|
| Formula |
(C21H27NO2)2. C4H6O6
|
|---|
| Exact mass |
800.4248
|
|---|
| Mol weight |
800.97
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
|
|---|
| Remark |
| Product (DG00292): | D01445<JP> |
|
|---|
| Efficacy |
Vasodilator (peripheral), alpha-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07235 | N-Methyl-D-aspartic acid (NMDA) receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C04 PERIPHERAL VASODILATORS
C04A PERIPHERAL VASODILATORS
C04AX Other peripheral vasodilators
C04AX28 Ifenprodil
D01445 Ifenprodil tartrate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
133 Vertigo agents
1339 Others
D01445 Ifenprodil tartrate (JP18)
2 Agents affecting individual organs
21 Cardiovascular agents
219 Miscellaneous
2190 Miscellaneous
D01445 Ifenprodil tartrate (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00292 Ifenprodil
D01445 Ifenprodil tartrate
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
DG00292 Ifenprodil
D01445 Ifenprodil tartrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D01445 Ifenprodil tartrate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01445 Ifenprodil tartrate
D01445 Ifenprodil tartrate tablets
D01445 Ifenprodil tartrate fine granules
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00292 Ifenprodil
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
DG00292 Ifenprodil
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 58
1 C8x C 17.9900 -14.9100
2 C8y C 17.9900 -16.3100
3 C8x C 19.1800 -17.0100
4 C8x C 20.4400 -16.3100
5 C8y C 20.4400 -14.9100
6 C8x C 19.1800 -14.2100
7 C1c C 21.6300 -14.2100
8 O1a O 16.8000 -17.0100
9 C1c C 22.8200 -14.9100
10 N1y N 24.0800 -14.2100
11 C1a C 22.8200 -16.3100
12 O1a O 21.6300 -12.8100
13 C1x C 25.2700 -14.9100
14 C1x C 26.4600 -14.2100
15 C1y C 26.4600 -12.8100
16 C1x C 25.2700 -12.1100
17 C1x C 24.0800 -12.8100
18 C1b C 27.7200 -12.1100
19 C8y C 28.9100 -12.8100
20 C8x C 28.9100 -14.2100
21 C8x C 30.1000 -14.9100
22 C8x C 31.3600 -14.2100
23 C8x C 31.3600 -12.8100
24 C8x C 30.1000 -12.1100
25 O6a O 33.7631 -14.0706
26 C6a C 34.9756 -14.7706
27 C1c C 36.1881 -14.0706
28 C1c C 37.4005 -14.7706
29 C6a C 38.6131 -14.0706
30 O6a O 39.8255 -14.7706
31 O6a O 34.9756 -16.1705
32 O1a O 36.1881 -12.6705
33 O1a O 37.4005 -16.1706
34 O6a O 38.6131 -12.6708
35 C8x C 17.9900 -14.9100
36 C8x C 19.1800 -14.2100
37 C8y C 20.4400 -14.9100
38 C8x C 20.4400 -16.3100
39 C8x C 19.1800 -17.0100
40 C8y C 17.9900 -16.3100
41 O1a O 16.8000 -17.0100
42 C1c C 21.6300 -14.2100
43 O1a O 21.6300 -12.8100
44 C1c C 22.8200 -14.9100
45 C1a C 22.8200 -16.3100
46 N1y N 24.0800 -14.2100
47 C1x C 25.2700 -14.9100
48 C1x C 26.4600 -14.2100
49 C1y C 26.4600 -12.8100
50 C1x C 25.2700 -12.1100
51 C1x C 24.0800 -12.8100
52 C1b C 27.7200 -12.1100
53 C8y C 28.9100 -12.8100
54 C8x C 28.9100 -14.2100
55 C8x C 30.1000 -14.9100
56 C8x C 31.3600 -14.2100
57 C8x C 31.3600 -12.8100
58 C8x C 30.1000 -12.1100
BOND 61
1 25 26 1
2 26 27 1
3 27 28 1
4 28 29 1
5 29 30 1
6 26 31 2
7 27 32 1 #Down
8 28 33 1 #Down
9 29 34 2
10 3 4 2
11 9 11 1
12 19 20 2
13 20 21 1
14 21 22 2
15 22 23 1
16 23 24 2
17 24 19 1
18 4 5 1
19 7 12 1
20 5 6 2
21 6 1 1
22 5 7 1
23 10 13 1
24 13 14 1
25 14 15 1
26 15 16 1
27 16 17 1
28 17 10 1
29 2 8 1
30 15 18 1
31 1 2 2
32 18 19 1
33 7 9 1
34 2 3 1
35 9 10 1
36 39 38 2
37 44 45 1
38 53 54 2
39 54 55 1
40 55 56 2
41 56 57 1
42 57 58 2
43 58 53 1
44 38 37 1
45 42 43 1
46 37 36 2
47 36 35 1
48 37 42 1
49 46 47 1
50 47 48 1
51 48 49 1
52 49 50 1
53 50 51 1
54 51 46 1
55 40 41 1
56 49 52 1
57 35 40 2
58 52 53 1
59 42 44 1
60 40 39 1
61 44 46 1
BRACKET 1 15.4700 -17.6400 15.4700 -11.6900
1 31.7800 -11.6900 31.7800 -17.6400
1 2
ORIGINAL 1 1 6 5 4 3 2 8 7 12 9 11 10 13 14 15 16
1 17 18 19 20 21 22 23 24
REPEAT 1 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
1 51 52 53 54 55 56 57 58
|
|---|