Entry |
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Name |
Finasteride (JAN/USP/INN); Propecia (TN); Proscar (TN) |
Product |
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Generic |
FINASTERIDE (A-S Medication Solutions), FINASTERIDE (A-S Medication Solutions), FINASTERIDE (A-S Medication Solutions), FINASTERIDE (A-S Medication Solutions), FINASTERIDE (A-S Medication Solutions), FINASTERIDE (A-S Medication Solutions), FINASTERIDE (A-S Medication Solutions), FINASTERIDE (Accord Healthcare), FINASTERIDE (Accord Healthcare), FINASTERIDE (American Health Packaging), FINASTERIDE (Aphena Pharma Solutions - Tennessee), FINASTERIDE (Aphena Pharma Solutions - Tennessee), FINASTERIDE (Ascend Laboratories), FINASTERIDE (Ascend Laboratories), FINASTERIDE (Asclemed USA), FINASTERIDE (Asclemed USA), FINASTERIDE (Asclemed USA), FINASTERIDE (Aurobindo Pharma Limited), FINASTERIDE (Aurobindo Pharma Limited), FINASTERIDE (AvPAK), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Bryant Ranch Prepack), FINASTERIDE (Burel Pharmaceuticals), FINASTERIDE (Camber Pharmaceuticals), FINASTERIDE (Camber Pharmaceuticals), FINASTERIDE (Cardinal Health 107), FINASTERIDE (Cipla USA), FINASTERIDE (Direct_Rx), FINASTERIDE (Dr Reddys Laboratories), FINASTERIDE (Dr Reddys Laboratories), FINASTERIDE (Dr. Reddy's Laboratories Limited), FINASTERIDE (Dr. Reddy's Laboratories Limited), FINASTERIDE (Exelan Pharmaceuticals), FINASTERIDE (Legacy Pharmaceutical Packaging), FINASTERIDE (Major Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (NuCare Pharmaceuticals), FINASTERIDE (Preferred Pharmacetucals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Preferred Pharmaceuticals), FINASTERIDE (Proficient Rx LP), FINASTERIDE (Proficient Rx LP), FINASTERIDE (Proficient Rx LP), FINASTERIDE (Proficient Rx LP), FINASTERIDE (QUALLENT PHARMACEUTICALS HEALTH LLC), FINASTERIDE (REMEDYREPACK), FINASTERIDE (REMEDYREPACK), FINASTERIDE (REMEDYREPACK), FINASTERIDE (REMEDYREPACK), FINASTERIDE (REMEDYREPACK), FINASTERIDE (REMEDYREPACK), FINASTERIDE (RedPharm Drug), FINASTERIDE (Rising Pharma Holdings), FINASTERIDE (Rising Pharma Holdings), FINASTERIDE (Sun Pharmaceutical Industries), FINASTERIDE (Sun Pharmaceutical Industries), FINASTERIDE (Teva Pharmaceuticals USA), FINASTERIDE (Thirty Madison), FINASTERIDE (Thirty Madison), FINASTERIDE (Zydus Lifesciences Limited), FINASTERIDE (Zydus Pharmaceuticals USA) |
Formula |
C23H36N2O2
|
Exact mass |
372.2777
|
Mol weight |
372.54
|
Structure |
|
Class |
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
Remark |
Therapeutic category: | 2499 |
Product (mixture): | D12486<US> |
|
Efficacy |
Antiandrogen, 5alpha-Reductase inhibitor |
Target |
|
Pathway |
|
Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D11 OTHER DERMATOLOGICAL PREPARATIONS
D11A OTHER DERMATOLOGICAL PREPARATIONS
D11AX Other dermatologicals
D11AX10 Finasteride
D00321 Finasteride (JAN/USP/INN) <JP/US>
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
G04CB Testosterone-5-alpha reductase inhibitors
G04CB01 Finasteride
D00321 Finasteride (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatological Agents, Other
Dermatological Agents, Miscellaneous
Finasteride
D00321 Finasteride (JAN/USP/INN)
Genitourinary Agents
Benign Prostatic Hypertrophy Agents
Finasteride
D00321 Finasteride (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
249 Miscellaneous
2499 Others
D00321 Finasteride (JAN/USP/INN)
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00321 Finasteride
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Dehydrogenases
SRD5A2
D00321 Finasteride (JAN/USP/INN) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00321
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00321
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Other DBs |
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LinkDB |
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KCF data |
ATOM 27
1 C1y C 25.2062 -19.0694
2 C1y C 24.0333 -19.7462
3 C1z C 25.2236 -17.7159
4 C1x C 27.5515 -19.0985
5 C1y C 22.8607 -19.0518
6 C1x C 24.0333 -21.1054
7 C1y C 26.4022 -17.0506
8 C1x C 24.0567 -17.0274
9 C1a C 25.2469 -16.2980
10 C1x C 27.5689 -17.7450
11 C1z C 21.6763 -19.7345
12 C1x C 22.8723 -17.6983
13 C1x C 22.8490 -21.7765
14 C5a C 26.3963 -15.6563
15 C1y C 21.6706 -21.0938
16 C2x C 20.4979 -19.0518
17 C1a C 21.6822 -18.3576
18 N1b N 25.2293 -14.9621
19 O5a O 27.5865 -14.9912
20 N1x N 20.4979 -21.7705
21 C2x C 19.3252 -19.7345
22 C1d C 24.0567 -14.1919
23 C5x C 19.3252 -21.0938
24 C1a C 22.9600 -13.5035
25 C1a C 23.2924 -15.2304
26 C1a C 24.8094 -13.0893
27 O5x O 18.1409 -21.7705
BOND 30
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 1 #Up
14 11 15 1
15 11 16 1
16 11 17 1 #Up
17 14 18 1
18 14 19 2
19 15 20 1
20 16 21 2
21 18 22 1
22 20 23 1
23 22 24 1
24 22 25 1
25 22 26 1
26 23 27 2
27 7 10 1
28 8 12 1
29 13 15 1
30 21 23 1
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