| Entry |
|
|---|
| Name |
Beclomethasone dipropionate (USP);
Beclometasone dipropionate (JP18);
Beclovent (TN);
Qnasl (TN);
Vanceril (TN) |
|---|
| Product |
|
|---|
| Formula |
C28H37ClO7
|
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| Exact mass |
520.2228
|
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| Mol weight |
521.04
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
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| Remark |
| Product (DG00097): | D00689<JP/US> D11572<US> |
|
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| Efficacy |
Antiasthmatic, Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Disease |
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
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| Interaction |
|
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA07 Beclometasone
D00689 Beclomethasone dipropionate (USP) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC15 Beclometasone
D00689 Beclomethasone dipropionate (USP) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD01 Beclometasone
D00689 Beclomethasone dipropionate (USP) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BA Glucocorticoids
R03BA01 Beclometasone
D00689 Beclomethasone dipropionate (USP) <JP/US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Anti-inflammatories, Inhaled Corticosteroids
Beclomethasone
D00689 Beclomethasone dipropionate (USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
132 Otic and nasal agents
1329 Others
D00689 Beclomethasone dipropionate (USP); Beclometasone dipropionate (JP18)
2 Agents affecting individual organs
22 Respiratory organ agents
229 Miscellaneous
2290 Miscellaneous
D00689 Beclomethasone dipropionate (USP); Beclometasone dipropionate (JP18)
24 Hormones
245 Adrenal hormone preparations
2459 Others
D00689 Beclomethasone dipropionate (USP); Beclometasone dipropionate (JP18)
Classification of Japanese OTC drugs [BR:br08313]
Agents for otolaryngologic use
70 Nasal sprays for inflammation
D00689 Beclomethasone dipropionate (USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Beclometasone dipropionate
D00689 Beclomethasone dipropionate (USP)
Second-class OTC drugs
Inorganic and organic chemicals
Beclometasone dipropionate
D00689 Beclomethasone dipropionate (USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00097 Beclometasone
D00689 Beclomethasone dipropionate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00689 Beclomethasone dipropionate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00689 Beclomethasone dipropionate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00689 Beclomethasone dipropionate (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00689 Beclometasone dipropionate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00689
Rx-to-OTC switch list in Japan [br08314.html]
D00689
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00097 Beclometasone
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 36
1 C1z C 23.0609 -16.7586
2 C1z C 21.8700 -17.4241
3 C1y C 24.2402 -17.4591
4 C5a C 23.0842 -14.9491
5 O7a O 24.2576 -16.0521
6 C1y C 21.8467 -18.7959
7 C1x C 20.6790 -16.7352
8 C1a C 21.8583 -16.0289
9 C1x C 24.2226 -18.8309
10 C1a C 25.4368 -18.1537
11 C1b C 21.8932 -14.2369
12 O5a O 24.2984 -14.2719
13 C7a C 25.6411 -16.0521
14 C1y C 20.6557 -19.4673
15 C1y C 19.4939 -17.4007
16 O7a O 20.6849 -14.9258
17 C1b C 26.3242 -14.8553
18 O6a O 26.3359 -17.2548
19 C1z C 19.4823 -18.7784
20 C1x C 20.6557 -20.8334
21 O1a O 18.3031 -16.7235
22 C7a C 19.4823 -14.2311
23 C1a C 27.7077 -14.8553
24 C1z C 18.2914 -19.4556
25 X Cl 19.4706 -20.1386
26 C1x C 19.4706 -21.5163
27 C1b C 18.2855 -14.9258
28 O6a O 19.4765 -12.8417
29 C2y C 18.2855 -20.8275
30 C2x C 17.1063 -18.7725
31 C1a C 18.2797 -18.0836
32 C1a C 17.0887 -14.2311
33 C2x C 17.1063 -21.5106
34 C2x C 15.9270 -19.4556
35 C5x C 15.9270 -20.8275
36 O5x O 14.7362 -21.5046
BOND 39
1 1 2 1
2 1 3 1
3 1 4 1 #Up
4 1 5 1 #Down
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 3 10 1 #Up
10 4 11 1
11 4 12 2
12 5 13 1
13 6 14 1
14 7 15 1
15 11 16 1
16 13 17 1
17 13 18 2
18 14 19 1
19 14 20 1
20 15 21 1 #Up
21 16 22 1
22 17 23 1
23 19 24 1
24 19 25 1 #Down
25 20 26 1
26 22 27 1
27 22 28 2
28 24 29 1
29 24 30 1
30 24 31 1 #Up
31 27 32 1
32 29 33 2
33 30 34 2
34 33 35 1
35 35 36 2
36 6 9 1
37 15 19 1
38 26 29 1
39 34 35 1
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