| Entry |
|
|---|
| Name |
Benzthiazide (JAN/INN);
Exna (TN) |
|---|
| Formula |
C15H14ClN3O4S3
|
|---|
| Exact mass |
430.9835
|
|---|
| Mol weight |
431.94
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
|---|
| Comment |
Thiazides
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D00651 Benzthiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D00651 Benzthiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D00651 Benzthiazide (JAN/INN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C8y C 23.6363 -18.5557
2 C8y C 23.6304 -17.1500
3 N5x N 22.4291 -19.2555
4 C8x C 24.8376 -19.2496
5 C8x C 24.8376 -16.4444
6 S2x S 22.4174 -16.4504
7 C8y C 21.2102 -18.5673
8 C8y C 26.0565 -18.5557
9 C8y C 26.0565 -17.1500
10 N4x N 21.2043 -17.1617
11 O3c O 23.6363 -15.7505
12 O3c O 21.2102 -15.7446
13 C1b C 20.0030 -19.2613
14 X Cl 27.2754 -19.2438
15 S4a S 27.2695 -16.4561
16 S2a S 18.7957 -18.5614
17 N1a N 28.4710 -15.7505
18 O3c O 28.2493 -17.4418
19 O3c O 26.2723 -15.4588
20 C1b C 17.5826 -19.2613
21 C8y C 16.3696 -18.5614
22 C8x C 15.1566 -19.2613
23 C8x C 16.3696 -17.1617
24 C8x C 13.9435 -18.5614
25 C8x C 15.1566 -16.4619
26 C8x C 13.9435 -17.1617
BOND 28
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 5 9 2
9 6 10 1
10 6 11 2
11 6 12 2
12 7 13 1
13 8 14 1
14 9 15 1
15 13 16 1
16 15 17 1
17 15 18 2
18 15 19 2
19 16 20 1
20 20 21 1
21 21 22 1
22 21 23 2
23 22 24 2
24 23 25 1
25 24 26 1
26 7 10 1
27 8 9 1
28 25 26 2
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