 | | DRUG: Clonidine hydrochloride | |
| Entry |
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| Name |
Clonidine hydrochloride (JP18/USP);
Nexiclon (TN);
Kapvay (TN);
Duraclon (TN);
Catapres (TN) |
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| Product |
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| Generic |
CLONIDINE (Ingenus Pharmaceuticals), CLONIDINE (PALMETTO PHARMACEUTICALS), CLONIDINE (TruPharma), CLONIDINE (XGen Pharmaceuticals DJB), CLONIDINE HCI (HF Acquisition Co LLC), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (Actavis Pharma), CLONIDINE HYDROCHLORIDE (Actavis Pharma), CLONIDINE HYDROCHLORIDE (Ajanta Pharma USA), CLONIDINE HYDROCHLORIDE (Alembic Pharmaceuticals Limited), CLONIDINE HYDROCHLORIDE (Alembic Pharmaceuticals), CLONIDINE HYDROCHLORIDE (American Health Packaging), CLONIDINE HYDROCHLORIDE (American Health Packaging), CLONIDINE HYDROCHLORIDE (Amneal Pharmaceuticals NY LLC), CLONIDINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CLONIDINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CLONIDINE HYDROCHLORIDE (Asclemed USA), CLONIDINE HYDROCHLORIDE (Asclemed USA), CLONIDINE HYDROCHLORIDE (Aurobindo Pharma Limited), CLONIDINE HYDROCHLORIDE (AvPAK), CLONIDINE HYDROCHLORIDE (BluePoint Laboratories), CLONIDINE HYDROCHLORIDE (BluePoint Laboratories), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Cardinal Health 107), CLONIDINE HYDROCHLORIDE (Coupler LLC), CLONIDINE HYDROCHLORIDE (Coupler LLC), CLONIDINE HYDROCHLORIDE (Coupler LLC), CLONIDINE HYDROCHLORIDE (Coupler LLC), CLONIDINE HYDROCHLORIDE (DirectRX), CLONIDINE HYDROCHLORIDE (DirectRX), CLONIDINE HYDROCHLORIDE (DirectRX), CLONIDINE HYDROCHLORIDE (Hikma Pharmaceuticals USA), CLONIDINE HYDROCHLORIDE (Lupin Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Major Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Method Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NCS HealthCare of KY), CLONIDINE HYDROCHLORIDE (NCS HealthCare of KY), CLONIDINE HYDROCHLORIDE (NCS HealthCare of KY), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Quality Care Products), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (RPK Pharmaceuticals), CLONIDINE HYDROCHLORIDE (RPK Pharmaceuticals), CLONIDINE HYDROCHLORIDE (RPK Pharmaceuticals), CLONIDINE HYDROCHLORIDE (RedPharm Drug), CLONIDINE HYDROCHLORIDE (Solco Healthcare LLC), CLONIDINE HYDROCHLORIDE (Solco Healthcare LLC), CLONIDINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CLONIDINE HYDROCHLORIDE (TruPharma), CLONIDINE HYDROCHLORIDE (Unichem Pharmaceuticals (USA)), CLONIDINE HYDROCHLORIDE (Xiamen LP Pharmaceutical), CLONIDINE HYDROCHLORIDE (Zydus Lifesciences Limited), CLONIDINE HYDROCHLORIDE (Zydus Pharmaceuticals USA), CLONIDINE HYDROCHLORIDE (medsource pharmaceuticals) |
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| Formula |
C9H9Cl2N3. HCl
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| Exact mass |
264.9940
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| Mol weight |
266.55
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG03231 Antihypertensive
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| Remark |
| Therapeutic category: | 2149 |
| Product (DG00249): | D00281<US> D00604<JP/US> |
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| Efficacy |
Antihypertensive, alpha2-Adrenergic receptor agonist |
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| Disease |
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| Comment |
Imidazoline derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING
C02AC Imidazoline receptor agonists
C02AC01 Clonidine
D00604 Clonidine hydrochloride (JP18/USP) <JP/US>
N NERVOUS SYSTEM
N02 ANALGESICS
N02C ANTIMIGRAINE PREPARATIONS
N02CX Other antimigraine preparations
N02CX02 Clonidine
D00604 Clonidine hydrochloride (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA04 Clonidine
D00604 Clonidine hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Antineoplastic Adjuncts/Mitigators
Clonidine
D00604 Clonidine hydrochloride (JP18/USP)
Cardiovascular Agents
Alpha-adrenergic Agonists
Clonidine
D00604 Clonidine hydrochloride (JP18/USP)
Central Nervous System Agents
Attention Deficit Hyperactivity Disorder Agents, Non-amphetamines
Clonidine
D00604 Clonidine hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D00604 Clonidine hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG00249 Clonidine
D00604 Clonidine hydrochloride
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG00249 Clonidine
D00604 Clonidine hydrochloride
DG03231 Antihypertensive
DG00249 Clonidine
D00604 Clonidine hydrochloride
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D00604 Clonidine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D00604 Clonidine hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00604 Clonidine hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG00249 Clonidine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG00249 Clonidine
DG03231 Antihypertensive
DG00249 Clonidine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 15
1 X Cl 21.5859 -16.5853
2 C8x C 12.8800 -15.9600
3 C8x C 12.8800 -17.3600
4 C8x C 14.0700 -18.0600
5 C8y C 15.3300 -17.3600
6 C8y C 15.3300 -15.9600
7 C8y C 14.0700 -15.2600
8 X Cl 16.5200 -18.0600
9 N1x N 17.7100 -17.3600
10 C2y C 17.7100 -15.9600
11 N2b N 16.5200 -15.2600
12 C1x C 19.0400 -17.7800
13 C1x C 19.8800 -16.6600
14 N1x N 19.0400 -15.5400
15 X Cl 14.0700 -13.8600
BOND 15
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 5 8 1
8 9 10 1
9 10 11 2
10 6 11 1
11 9 12 1
12 12 13 1
13 13 14 1
14 10 14 1
15 7 15 1
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