| Entry |
|
|---|
| Name |
demethylsterigmatocystin 6-O-methyltransferase;
demethylsterigmatocystin methyltransferase;
O-methyltransferase I
|
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
|
|---|
| Sysname |
S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase
|
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + 6-demethylsterigmatocystin = S-adenosyl-L-homocysteine + sterigmatocystin [RN: R03112]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
6-demethylsterigmatocystin [CPD: C03683]
|
|---|
| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
sterigmatocystin [CPD: C00961]
|
|---|
| Comment |
Dihydrodemethylsterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi.
|
|---|
| History |
EC 2.1.1.109 created 1992
|
|---|
| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
|
|---|
| Orthology |
| K17649 | demethylsterigmatocystin 6-O-methyltransferase |
|
|---|
| Genes |
| MBRN: | 26243136(aflO_1) 26247609(lepI) |
| ALUC: | AKAW2_20291A AKAW2_60089S |
| APUU: | APUU_20054A APUU_50253S APUU_50657S |
| ADAC: | 96080480(ACET3X_000158) 96080555(ACET3X_000233) 96089010(ACET3X_008688) 96089949(ACET3X_009627) |
|
|---|
| Reference |
|
|---|
| Authors |
Yabe K, Ando Y, Hashimoto J, Hamasaki T. |
|---|
| Title |
Two distinct O-methyltransferases in aflatoxin biosynthesis. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.109 |
|
|---|
| LinkDB |
|
|---|