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KEGG   ENZYME: 2.1.1.50
Entry
EC 2.1.1.50                 Enzyme                                 
Name
loganate O-methyltransferase;
loganate methyltransferase;
S-adenosyl-L-methionine:loganic acid methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:loganate 11-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin [RN:R03554]
Reaction(KEGG)
R03554;
(other) R05834
Substrate
S-adenosyl-L-methionine [CPD:C00019];
loganate [CPD:C01512]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
loganin [CPD:C01433]
Comment
Also acts on secologanate. Methylates the 11-carboxy group of the monoterpenoid loganate.
History
EC 2.1.1.50 created 1976
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:4698228]
  Authors
Madyastha KM, Guarnaccia R, Baxter C, Coscia CJ.
  Title
S-Adenosyl-L-methionine: loganic acid methyltransferase. A carboxyl-alkylating enzyme from Vinca rosea.
  Journal
J Biol Chem 248:2497-501 (1973)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.50
IUBMB Enzyme Nomenclature: 2.1.1.50
ExPASy - ENZYME nomenclature database: 2.1.1.50
BRENDA, the Enzyme Database: 2.1.1.50
CAS: 39391-10-1
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